Publications by authors named "Rawya Mohamed Salih Ibrahim"
Article Synopsis
- Gut dysbiosis and gut-brain-axis dysregulation are linked to hypertension, and Vitamin C (VC) has potential anti-hypertensive effects in hypertensive rats.
- A study showed that daily VC intake (200 or 1000 mg/kg) improved blood pressure, gut microbiota diversity, and gut health in spontaneously hypertensive rats after 4 weeks.
- The findings suggest that VC’s anti-hypertensive effects may stem from its ability to reshape gut microbiota and reduce inflammation and oxidative stress in the brain region responsible for blood pressure regulation.
Aims: Exercise and food supplement of vitamin C (VC) are beneficial to human health, especially for those who suffer from hypertension. Here we tend to explore if gut microflora is involved in the anti-hypertensive effects of exercise and VC-supplement therapies.
Materials And Methods: With the spontaneously hypertensive rat (SHR) model, the small intestine pathology and the fecal microbiota was analyzed along with the pro- and anti-inflammatory cytokines (PICs and AICs) and reactive oxygen species (ROS) in the hypothalamus paraventricular nucleus (PVN) and intestine.