Publications by authors named "Rawiwan Watanadilok"
Article Synopsis
- Clionasterol, clionasterol monoacetate, and other sterols from the marine sponge Xestospongia exigua were tested for their effects on the human complement system.
- All sterols showed a dose-dependent inhibition of the classical pathway (CP) but had no effect on the alternative pathway (AP) at high concentrations.
- Clionasterol was identified as the most potent inhibitor of CP, effectively targeting complement component C1, while the presence of an epidioxy group in another compound reduced its inhibitory effectiveness.
Further halotyrosine derivatives from the marine sponge Suberea aff. praetensa.
Z Naturforsch C J Biosci
October 2002
Reexamination of the marine sponge Suberea aff. praetensa, (Row) from the Gulf of Thailand furnished in addition to bromotyrosine derivatives found previously 5-bromo- and 5-chlorocavernicolin, cavernicolins 1 and 2, two other brominated tyrosine metabolites, a known bisoxazolidone and a new unusual rearranged tyrosine metabolite subereatensin. Several of the metabolites exhibited significant inhibitory effects against five human cancer cell lines.
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