Effect of Chronic Rhinitis Treatment in Children with Attention-Deficit/Hyperactivity Disorder.

Objective: The purpose of this study is to examine the effect of chronic rhinitis treatment on attention-deficit/hyperactivity disorder (ADHD) symptoms in children with ADHD.

Methods: Children and adolescents with ADHD were screened for chronic rhinitis symptoms. Participants with positive chronic rhinitis screening underwent the skin prick test and received rhinitis treatment for 3 months.

Effect of Iron Supplementation in Children with Attention-Deficit/Hyperactivity Disorder and Iron Deficiency: A Randomized Controlled Trial.

Objectives: To determine the effectiveness of combined iron supplementation and methylphenidate treatment on attention-deficit/hyperactivity disorder (ADHD) symptoms in children/adolescents with ADHD and iron deficiency compared with methylphenidate alone.

Methods: In total, 116 children/adolescents with ADHD were screened for iron deficiency. Participants who exhibited iron deficiency were randomized into 2 groups (ferrous supplementation vs placebo).

Chromosomal microarray analysis in a cohort of underrepresented population identifies SERINC2 as a novel candidate gene for autism spectrum disorder.

Chromosomal microarray (CMA) is now recognized as the first-tier genetic test for detection of copy number variations (CNVs) in patients with autism spectrum disorder (ASD). The aims of this study were to identify known and novel ASD associated-CNVs and to evaluate the diagnostic yield of CMA in Thai patients with ASD. The Infinium CytoSNP-850K BeadChip was used to detect CNVs in 114 Thai patients comprised of 68 retrospective ASD patients (group 1) with the use of CMA as a second line test and 46 prospective ASD and developmental delay patients (group 2) with the use of CMA as the first-tier test.

Emergent Literacy in Thai Preschoolers: A Preliminary Study.

Objective: To investigate emergent literacy skills, including phonological awareness when presented with an initial phoneme-matching task and letter knowledge when presented with a letter-naming task in Thai preschoolers, and to identify key factors associated with those skills.

Methods: Four hundred twelve typically developing children in their final kindergarten year were enrolled in this study. Their emergent reading skills were measured by initial phoneme-matching and letter-naming tasks.

Parents' Evaluation of Developmental Status (PEDS) in Screening for Developmental Delay in Thai Children Aged 18-30 Months.

The PEDS-Thai is a developmental screening tool. We studied its diagnostic performance among 137 Thai children (48.9%) aged 18-30 month.

Ramathibodi Language Development Questionnaire: A Newly Developed Screening Tool for Detection of Delayed Language Development in Children Aged 18-30 Months.

Objective: To develop a parental questionnaire for screening children with delayed language development in primary care settings.

Material And Method: Ramathibodi Language Development (RLD) questionnaire was developed and completed by groups of 40 typically developing children age 18 to 30 months old and 30 children with delayed language development.

Results: The mean score was significantly lower in the delay language group (6.

A new structured interview for children with autism spectrum disorder based on the DSM-IV.

Background: Autism spectrum disorder (ASD) is a common neurodevelopmental disorder in children. The clinical spectrum of ASD includes autism, childhood disintegrative disorder Asperger syndrome and pervasive developmental disorder not otherwise specified (PDD-NOS). Although the DSM-IVcriteria are well acceptedforASD diagnosis, there are some known limitations for clinicians.

Impaired picture sequencing ability in children with premature birth.

Background: Children born preterm are at increased risk for executive dysfunction, which affects learning outcomes. Picture sequencing ability is considered as executive function (EF) that requires skills in working memory and organizing the pictures. Children born preterm might have difficulties in these skills.

A case with a ring chromosome 13 in a cohort of 203 children with non-syndromic autism and review of the cytogenetic literature.

Autistic spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by impairments of social interaction, communication and restricted, repetitive and stereotyped patterns of behavior, interests and activities. Frequencies of chromosomal abnormalities in cohorts of individuals with ASD varying between 1.2 and 28.

Mutation screening of the neurexin 1 gene in thai patients with intellectual disability and autism spectrum disorder.

Aim: Neurexin 1 has two major protein isoforms using alternative promoters, coding for the alpha-neurexin 1 (α-NRXN1) and beta-neurexin 1 (β-NRXN1) genes. This study is to explore the possibility that variants of the NRXN1 gene predispose to intellectual disability (ID) and autism spectrum disorder (ASD).

Methods: The coding regions in 24 exons and exon-intron boundaries of the NRXN1 gene were investigated in 115 Thai patients with ID and ASD by direct DNA sequencing.

Translation and validation of the Children's Communication Checklist to evaluate pragmatic language impairment in Thai children.

Background: The Children's Communication Checklist (CCC) was developed to provide an assessment of domains of language impairment in children, particularly the pragmatic domain. This study examined the effectiveness of the CCC-Thai version in discriminating children with autism spectrum disorders (ASD) from typically developing children.

Methods: The parents of two groups of 50 children aged 4-6 years, one with clinically ascertained ASD, and one with typical development, completed the CCC-Thai version.

Language development among the siblings of children with autistic spectrum disorder.

Language development in 32 preschool siblings (aged 2-6 years) of children with diagnosed autistic spectrum disorder (ASD) was compared with that of a control group of 28 typical preschool children. Groups were matched by siblings' age, gender, maternal educational level and family income. The mean ages of the siblings group and the control group were 4.

Comparison of mental health symptoms between children attending developmental/behavioural paediatric clinics and child and adolescent mental health service.

Aim: Australian paediatricians are being referred many children with severe and complex behavioural presentations. Australian paediatricians are being referred many children with severe and complex behavioural presentations. The aim of this study was to compare patients seen in the developmental/behavioural paediatric clinic (DBP) with those seen in the community child and adolescent mental health service (CAMHS) of a paediatric teaching hospital.

Effect of oral vitamin E supplementation in children with cholestasis.

Objective: Malabsorption and deficiency of vitamin E are common consequences of chronic cholestasis. The objective of this study was to determine vitamin E status by using plasma vitamin E/total lipid ratio (E/L) in children with cholestasis during supplementation with 20 IU/kg/day and 100 IU/kg/day of oral vitamin E capsule, and 50 IU/kg/day of cold water soluble form (CWSIF) of vitamin E.

Method: Children with cholestasis who were being supplemented with 20 IU/kg/day of oral vitamin E capsule (dl-alpha-tocopherol) were enrolled into this study.

Prevalence and clinical characteristics of dyslexia in primary school students.

Background: Dyslexia is the most common subtype of learning disabilities with a prevalence ranging from 5-10 per cent. The central difficulty in dyslexia is the phonological awareness deficit. The authors have developed a screening test to assess the reading ability of Thai primary school students.