Background And Aim: Among the cardiovascular diseases (CVDs), heart failure, hypertension, and myocardial infarction are associated with the greatest number of disability-adjusted life years due to lifestyle changes and the failure of therapeutic approaches, especially the one-size-fits-all interventions. As a result, there has been advances in defining genetic variants responsible for different responses to cardiovascular drugs such as antiplatelets, anticoagulants, statins, and beta-blockers, which has led to their usage in guiding treatment plans. This study comprehensively reviews the current state-of-the-art potential of pharmacogenomics in dramatically altering CVD treatment.
View Article and Find Full Text PDFAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that can present with motor and extra-motor manifestations. Its global prevalence is 4.42 per 1 000 000, and it has a high mortality rate.
View Article and Find Full Text PDFTo measure the mental health effects (perceived stress, anxiety, and depression) among health care workers and medical students in Lebanon during the coronavirus disease 2019 (COVID-19) pandemic and subsequent to the Beirut blast. In this cross-sectional study, a self-administered online questionnaire was developed and distributed between late December 2020 and early February 2021 among health care workers and medical students via social media. The 10-item Perceived Stress Scale (PSS-10) and the 4-item Patient Health Questionnaire for Depression and Anxiety (PHQ-4) were administered.
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