Effect of bone-marrow-derived mesenchymal stem cells on the rate of orthodontic tooth movements in rabbits.

Unlabelled: Mesenchymal stem cells from bone marrow, such as bone marrow aspirate concentrate (BMAC) and cultured and isolated bone marrow mesenchymal stem cells (BM-MSCs), have been used as therapeutic alternatives to enhance remodeling in the bone.

Objective: This study aimed to evaluate the effects of BMAC and BM-MSCs on orthodontic tooth movements in rabbits.

Methods: A100- gram nickel-titanium closed-coil springs were used to initiate orthodontic tooth movement of the lower first premolars in 35 male New Zealand rabbits for 21 days.