Publications by authors named "Rawan Nawabit"
Article Synopsis
- The study investigates the effects of reduced-intensity conditioning (RIC) regimens on fertility and gonadal function in adolescent and young adult survivors of hematopoietic stem cell transplantation (HCT).
- Researchers analyzed data from 326 patients aged 10 to 40 who underwent their first allogeneic HCT, focusing on hormonal levels as indicators of fertility potential and gonadal failure.
- Findings revealed that a significant majority of female HCT recipients had very low levels of AMH, indicating poor fertility potential, and that RIC might have a lower incidence of detectable AMH compared to myeloablative conditioning (MAC), although impairment was still common.
Background: Group 1 pulmonary arterial hypertension (PAH) is a progressive fatal condition characterized by right ventricular (RV) failure with worse outcomes in connective tissue disease (CTD). Obstructive sleep apnea and sleep-related hypoxia may contribute to RV dysfunction, though the relationship remains unclear.
Objectives: The aim of this study was to prospectively evaluate the association of the apnea-hypopnea index (AHI) and sleep-related hypoxia with RV function and survival.
Article Synopsis
- PVDOMICS is a precision medicine initiative aimed at understanding pulmonary vascular disease (PVD) by combining clinical measurements with omic data to improve classification.
- The study involved 1,193 subjects, including different groups of pulmonary hypertension (PH), comparators with mild disease, and healthy controls; findings showed notable differences in symptoms and survival rates among the groups.
- Key results highlighted low diffusing capacity for carbon monoxide and enlarged right atrial volume in certain PH groups, frequent ground glass opacities on CT scans, and the worst transplant-free survival in group 3 PH.
Study Objectives: This preliminary study investigated the tolerability and efficacy of a novel mattress technology-the Sound-To-Sleep (STS) system-in the treatment of sleep problems in children with autism.
Methods: After screening, 45 children, ages 2.5 to 12.
Rationale: Sleep-disordered breathing recurrent intermittent hypoxia and sympathetic nervous system activity surges provide the milieu for cardiac arrhythmia development.
Objective: We postulate that the prevalence of nocturnal cardiac arrhythmias is higher among subjects with than without sleep-disordered breathing.
Methods: The prevalence of arrhythmias was compared in two samples of participants from the Sleep Heart Health Study frequency-matched on age, sex, race/ethnicity, and body mass index: (1) 228 subjects with sleep-disordered breathing (respiratory disturbance index>or=30) and (2) 338 subjects without sleep-disordered breathing (respiratory disturbance index<5).