Publications by authors named "Rawan Moustafa"
Background: Collateral status (CS) plays a crucial role in infarct growth rate, risk of postthrombectomy hemorrhage, and overall clinical outcomes in patients with acute ischemic stroke (AIS) secondary to anterior circulation large-vessel occlusions (LVOs). Hypoperfusion intensity ratio has been previously validated as an indirect noninvasive pretreatment imaging biomarker of CS. In addition to imaging, derangements in admission laboratory findings can also influence outcomes in patients with AIS-LVO.
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- Acute ischemic stroke (AIS) patients' collateral status (CS) is a crucial factor in predicting favorable outcomes, with relative cerebral blood flow (rCBF) being a key measurement for evaluating CS.
- A study analyzing 221 AIS patients found that factors like male gender, chronic kidney disease, higher stroke severity (NIH Stroke Scale score ≥12), and low systolic blood pressure (<140) are linked to poor collateral status (rCBF <38%).
- The findings emphasize the importance of these baseline characteristics and lab values in determining the severity of collateral blood flow and potential patient outcomes in AIS due to large vessel occlusion.