Publications by authors named "Ravul Jindal"

Article Synopsis
  • Chronic Limb Threatening Ischemia (CLTI) is a severe condition leading to high rates of limb amputation and cardiovascular death, particularly in cases where standard treatments fail.
  • Endovascular interventions are the main treatment strategy, but a significant number of patients are considered "no-option," prompting interest in new therapies like bone marrow-derived mesenchymal stromal cells (BM-MSC).
  • REGENACIP is an approved BM-MSC therapy in India for patients with critical limb ischemia who are not candidates for traditional revascularization, and this review discusses its potential benefits and effectiveness in treating CLTI.
View Article and Find Full Text PDF

Background: Inadvertent intra-arterial injection of sclerosants is an uncommon adverse event of both ultrasound-guided and direct vision sclerotherapy. This complication can result in significant tissue or limb loss and significant long-term morbidity.

Objectives: To provide recommendations for diagnosis and immediate management of an unintentional intra-arterial injection of sclerosing agents.

View Article and Find Full Text PDF

Uterine arteriovenous malformations (UAVMs) are rare and abnormal entanglements of uterine arteries and veins that are potentially fatal, requiring blood transfusions in about a third of cases. Although the optimal management of the condition is not well established in the literature, surgical hysterectomy is believed to be the only definitive treatment for arteriovenous malformations. We present three cases of UAVMs treated by a minimally invasive endovascular approach.

View Article and Find Full Text PDF
Article Synopsis
  • * A systematic review of studies on veno-active drugs (VADs) revealed that only specific treatments like micronized purified flavonoid fraction (MPFF), aminaphthone, and low-dose diosmin showed statistically significant improvements in HRQoL compared to placebo.
  • * The research included data from various sources, highlighting a discrepancy between patient and physician perceptions regarding the impact of CVD, where physicians often underestimate the emotional and physical toll on patients.
View Article and Find Full Text PDF

Chemoports are often required for oncological patients requiring repeated blood draws and long-term drug therapy. However, complications such as dislodgement, fracture, thrombosis, and venous occlusion may occur if the ports remain unremoved when not in use. Nonetheless, existing techniques require multiple accesses or release of the stuck catheter tip to retrieve the catheter, making the procedure inconvenient.

View Article and Find Full Text PDF

BACKGROUND Thrombosis with thrombocytopenia syndrome (TTS), including vaccine-induced immune thrombotic thrombocytopenia (VITT), is an extremely rare adverse effect, mostly seen after initial vaccination with the viral vector-based AstraZeneca-Oxford COVID-19 vaccine. It is characterized by mild to severe thrombocytopenia and venous or arterial thrombosis. CASE REPORT Herein, we present a case of an 18-year-old male patient who developed Level 1 TTS (probable VITT) eight days after immunization with the ChADOx1 nCOV-19 vaccine (Covishield; AZ-Oxford).

View Article and Find Full Text PDF

Published scientific evidence demonstrate the current spread of healthcare misinformation in the most popular social networks and unofficial communication channels. Up to 40% of the medical websites were identified reporting inappropriate information, moreover being shared more than 450,000 times in a 5-year-time frame. The phenomenon is particularly spread in infective diseases medicine, oncology and cardiovascular medicine.

View Article and Find Full Text PDF

Venous ulcer is an extremely common aetiology of lower extremity ulceration, which affects approximately 1% population in most of the countries, and the incidence rate increases with age and female gender. Proper assessment and diagnosis of both the patient and ulcer are inevitable in order to differentiate venous ulcers from other lower extremity ulceration and to frame an adequate and individualised management plan. Venous ulcers generally persist for weeks to many years and are typically recurrent in nature.

View Article and Find Full Text PDF

Introduction Despite a marked recent increase in the number of publications describing the incidence of venous thromboembolism (VTE) in Asia, and especially in mainland China, Hong Kong, Taiwan, Korea, Japan and Singapore, there remains a lack of consensus on the true risks, and trends over time, to inform appropriate clinical practice. The purpose of this systematic review was therefore to examine evidence about the incidence of symptomatic VTE in Asia. Methods Databases were searched for studies from Asia, published between January 1995 and February 2016, on the incidence of symptomatic VTE, deep vein thrombosis (DVT) or pulmonary embolism.

View Article and Find Full Text PDF

Hypernatremic dehydration in breast fed neonates is a rare but increasingly recognized problem. If not identified early, it may lead to potentially life threatening complications. The authors describe a neonate who developed thrombosis and lower limb ischemia secondary to hypernatremic dehydration.

View Article and Find Full Text PDF

The purpose of this study was to demonstrate the use of endovascular technology in the management of peripheral infected aneurysms in high-risk patients as a temporary measure or definitive solution. Five cases underwent successful endovascular stenting of infected aneurysms of the subclavian, femoral, and carotid arteries. All these patients were at high risk for open surgery.

View Article and Find Full Text PDF

Cystic adventitial disease is a rare disease affecting mainly young males. We describe two patients with this disease affecting the iliofemoral artery. These reports reemphasize the importance of keeping cystic adventitial disease as a differential diagnosis in young patients who present with leg ischemia.

View Article and Find Full Text PDF

Background: Pancreatic necrosectomy for necrotizing pancreatitis is a formidable operation. There are limited data from the Indian subcontinent regarding outcome and recent trends in management.

Methods: Patients undergoing pancreatic necrosectomy over a 12-year period were identified from a prospective database.

View Article and Find Full Text PDF

A 22-year-old woman with a diagnosis of Klippel-Trenaunay syndrome presented with pain in the left hypochondrium and vomiting. Investigations revealed a huge splenomegaly with multiple hypodense lesions and irregular, linearly enhanced areas. She underwent splenectomy and had good postoperative recovery.

View Article and Find Full Text PDF

Background: Pulmonary complications remain a leading cause of morbidity after major abdominal operations.

Objective: To compare pulmonary function and the frequency of pulmonary complications after laparoscopic cholecystectomy (LC) and open cholecystectomy (OC).

Methods: Fifty-five patients with symptomatic gallstone disease undergoing elective cholecystectomy (LC 40, OC 15) under general anesthesia were evaluated using pulmonary function tests (forced vital capacity [FVC], forced expiratory volume at 1 second [FEV1], and forced expiratory flow at 25% to 75% [FEF25% -75%], chest X-ray and pulse oximetry before and after surgery.

View Article and Find Full Text PDF

This is a retrospective study of the experience with extremity vascular trauma at a tertiary level referral centre in North India where the majority of the population lives in villages and the incidence of high-speed automobile accidents and civilian violence is low. The aim was to study the aetiology, pattern of injuries and the mortality and morbidity rates due to vascular trauma in our population. Data relating to 148 patients presenting with vascular trauma requiring surgical intervention other than amputation between January 1996 and December 2002 were collected retrospectively.

View Article and Find Full Text PDF

Background And Aim: Surgery for pancreatic necrosis complicating acute severe pancreatitis carries a high risk of morbidity and mortality. We evaluated the efficacy of necrosectomy and closed lesser sac lavage as a method of management of pancreatic necrosis.

Methods: Fifty-eight patients with pancreatic necrosis who underwent pancreatic necrosectomy consecutively in a tertiary care referral center were retrospectively analyzed.

View Article and Find Full Text PDF

Background: Vascular complications resulting from i.v. drug abuse constitute a range of clinical problems from simple to serious.

View Article and Find Full Text PDF