Publications by authors named "Raviprasenna Parasuraman"
Rabbit antithymocyte globulin is a lymphocytedepleting agent commonly used as induction therapy in kidney transplants. Although its use is generally safe and well tolerated, serious side effects can occur. Here, we describe a case of a severe immune complex hypersensitivity reaction with disseminated intravascular coagulation in response to rabbit antithymocyte globulin infusion.
View Article and Find Full Text PDFIntroduction: Pulmonary hypertension is common among patients with end-stage renal disease, although data regarding the impact of right ventricular (RV) failure on postoperative outcomes remain limited. We hypothesized that echocardiographic findings of RV dilation and dysfunction are associated with adverse clinical outcomes after renal transplant.
Methods: A retrospective review of adult renal transplant recipients at a single institution from January 2008 to June 2010 was conducted.
Article Synopsis
- Kidney transplantation (KT) is the preferred treatment for end-stage kidney disease (ESKD), improving survival and quality of life compared to dialysis, but cardiovascular disease (CVD) remains a major challenge for patients post-transplant.
- KT recipients face various CVD risks, including coronary artery disease and heart failure, which are worsened by factors like obesity and the effects of immunosuppressive medications.
- The review calls for more research on CVD in KT patients and advocates for a collaborative 'cardio-nephrology' care model to improve patient outcomes and reduce cardiovascular complications following transplantation.
Background: Renal angiography (RA) is considered to be the gold standard for the diagnosis of renal artery stenosis (RAS). However, it is invasive and potentially harmful; hence there is a need for an optimal noninvasive test. Magnetic resonance angiography (MRA) is currently accepted as the optimal noninvasive test by many.
View Article and Find Full Text PDFThrombotic microangiopathy (TMA) in renal transplant recipients is commonly associated with calcineurin inhibitors (CNIs), though several factors such as vascular rejection, viral infections and other drugs may play a contributory role. We report a series of 29 patients with TMA, all of whom were on CNIs. Though plasma exchange (PEx) is widely used to treat TMA, therapeutic guidelines are not well defined.
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