Causal contextual bandits with one-shot data integration.

We study a contextual bandit setting where the agent has access to causal side information, in addition to the ability to perform multiple targeted experiments corresponding to potentially different context-action pairs-simultaneously in one-shot within a budget. This new formalism provides a natural model for several real-world scenarios where parallel targeted experiments can be conducted and where some domain knowledge of causal relationships is available. We propose a new algorithm that utilizes a novel entropy-like measure that we introduce.

Betanin inspired zinc oxide nanoparticles: The potential antioxidant and anticancer activity against human lung cancer cell line (A549).

Background Information: Lung cancer is the most frequently reported disease on a global scale. The bioactive substances are less successful in specifically destroying cancer cells. To prevent early inactivation and ensure targeted delivery of bioactive chemicals to cancer cells.

Active learning with human heuristics: an algorithm robust to labeling bias.

Active learning enables prediction models to achieve better performance faster by adaptively querying an oracle for the labels of data points. Sometimes the oracle is a human, for example when a medical diagnosis is provided by a doctor. According to the behavioral sciences, people, because they employ heuristics, might sometimes exhibit biases in labeling.

Machine learning identifies cytokine signatures of disease severity and autoantibody profiles in systemic lupus erythematosus - a pilot study.

Disrupted cytokine networks and autoantibodies play an important role in the pathogenesis of systemic lupus erythematosus. However, conflicting reports and non-reproducibility have hindered progress regarding the translational potential of cytokines in SLE. This study attempts to address the existing knowledge gap using multiplex cytokine assay and machine learning.

Efficacy of the Coronoid Notch and Occlusal Plane As Predictable Landmarks for Determining the Medial Cut Height in Bilateral Sagittal Split Osteotomy: A Split-Mouth Observational Study.

Aim: This split-mouth observational study was conducted to assess the reliability and safety of using the coronoid notch and occlusal plane as landmarks to aid surgeons during bilateral sagittal split osteotomy (BSSO).

Materials And Methods: Thirteen patients between the ages of 18 and 30 years, with class II and class III mandibular skeletal malocclusion requiring BSSO, were randomly selected and assigned to each of the study and control groups. A split-mouth study was chosen to conduct this research.

Comparative genome analysis reveals putative and novel antimicrobial resistance genes common to the nosocomial infection pathogens.

The 21st century has witnessed several clinical outcomes regarding AMR. One health concept has been foreseen as a standard global public health initiative in ensuring human, animal and environmental health. The present study explores critical Gram-negative ESKAPE pathogens encompassing Acinetobacter baumannii (ACB), Klebsiella pneumoniae (KPX) and Pseudomonas aeruginosa (PAE).

How Effective is Deep Inspiration Breath Hold in Minimizing Cardiac Doses During Hybrid Radiotherapy Treatment for Left-Sided Breast Cancer with Comprehensive Regional Nodes?

Background: In the context of left breast cancer radiotherapy, long term cardiopulmonary toxicity has been well-documented, significant efforts have been undertaken to mitigate such toxicity by using 4D gating, deep inspiration breath-hold(DIBH) and active breath control(ABC) techniques.

Purpose: To evaluate and compare the cardio-pulmonary radiation doses incurred during postmastectomy radiotherapy (PMRT) in two distinct breathing conditions such as DIBH and Free Breathing (FB), with a specific focus on the left chest wall with comprehensive regional nodal irradiation.

Materials And Methods: A prospective dosimetric study was conducted on 15 patients who received adjuvant loco-regional radiotherapy of chest-wall (CW), supraclavicular fossa(SCF), and internal mammary region(IMC), with or without axilla.

Plasmodium berghei HMGB1 controls the host immune responses and splenic clearance by regulating the expression of pir genes.

High mobility group box (HMGB) proteins belong to the high mobility group (HMG) superfamily of non-histone nuclear proteins that are involved in chromatin remodeling, regulation of gene expression, and DNA repair. When extracellular, HMGBs serve as alarmins inducing inflammation, and this is attributed to the proinflammatory activity of box B. Here, we show that Plasmodium HMGB1 has key amino acid changes in box B resulting in the loss of TNF-α stimulatory activity.

Pyrolysis behaviour and synergistic effect in co-pyrolysis of wheat straw and polyethylene terephthalate: A study on product distribution and oil characterization.

Renewable lignocellulosic biomass is a favorable energy resource since its co-pyrolysis with hydrogen-rich plastics can produce high-yield and high-quality biofuel. In contrast to earlier co-pyrolysis research that concentrated on increasing product yield, this study comprehends the synergistic effects of two distinct feedstocks that were not considered earlier. This work focuses on co-pyrolyzing wheat straw (WS) with non-reusable polyethylene terephthalate (PET) for the production of pyrolysis oil.

Photocatalytic degradation of rhodamine B dye pollutants by FeO/SiO core-shell magnetic nanocomposite functionalized with TiO.

Significant efforts have been dedicated to creating recyclable and efficient methods for treating waste dyes, including rhodamine B (RhB). Nevertheless, challenges such as complex operational techniques, high costs, energy consumption, and inefficacy in dye removal persist. Here, the synthesis and application of TiO/FeO/SiO for photocatalytic degradation of RhB dye pollutants have been explored.

Changes in microbial dynamics and fermentation characteristics of alfalfa silage: A potent approach to mitigate greenhouse gas emission through high-quality forage silage.

Feeding ruminants with high-quality forage can enhance digestibility and reduce methane production. Development of high-quality silage from leguminous plants with lactic acid bacteria can improve digestibility and it mitigate the greenhouse gas emissions. In this study, we developed a high-quality alfalfa silage with improved fermentation index and microbial dynamics using Levilactobacillus brevis-KCC-44 at low or high moisture (LM/HM) conditions and preserved it for 75 or 150 days.

Assessment of growth, reproduction, and vermi-remediation potentials of Eisenia fetida on heavy metal exposure.

Heavy metal pollution is a significant environmental concern with detrimental effects on ecosystems and human health, and traditional remediation methods may be costly, energy-intensive, or have limited effectiveness. The current study aims were to investigate the impact of heavy metal toxicity in Eisenia fetida, the growth, reproductive outcomes, and their role in soil remediation. Various concentrations (ranging from 0 to 640 mg per kg of soil) of each heavy metal were incorporated into artificially prepared soil, and vermi-remediation was conducted over a period of 60 days.

A Comparative Assessment of Right-Angle Screwdriver Versus Conventional Screwdriver for Orthognathic Surgeries.

Background Bilateral orthognathic surgery is one of the unique and challenging orthognathic surgeries that gained popularity after numerous modifications to the techniques. Using linear equipment inside the oral cavity might lead to malalignment or structural weakness due to incorrect placement, making the ramus osteotomy more difficult. By directly positioning the instrument perpendicularly over the mandibular ramus region, a right-angle drill can help promote a more ergonomic approach.

Futuristic advancements in phytoremediation of endocrine disruptor Bisphenol A: A step towards sustainable pollutant degradation for rehabilitated environment.

Bisphenol A (BPA) accumulates in the environment at lethal concentrations because of its high production rate and utilization. BPA, originating from industrial effluent, plastic production, and consumer products, poses serious risks to both the environment and human health. The widespread aggregation of BPA leads to endocrine disruption, reactive oxygen species-mediated DNA damage, epigenetic modifications and carcinogenicity, which can disturb the normal homeostasis of the body.

Efficient photocatalytic bactericidal performance of green-synthesised TiO/reduced graphene oxide using banana peel extracts.

In this study, the fabrication of titanium dioxide/reduced graphene oxide (TiO/rGO) utilising banana peel extracts ( L.) as a reducing agent for the photoinactivation of () and () was explored. The GO synthesis was conducted using a modified Tour method, whereas the production of rGO involved banana peel extracts through a reflux method.

Plant glucosinolate biosynthesis and breakdown pathways shape the rhizosphere bacterial/archaeal community.

Rhizosphere microbial community assembly results from microbe-microbe-plant interactions mediated by small molecules of plant and microbial origin. Studies with Arabidopsis thaliana have indicated a critical role of glucosinolates in shaping the root and/or rhizosphere microbial community, likely through breakdown products produced by plant or microbial myrosinases inside or outside of the root. Plant nitrile-specifier proteins (NSPs) promote the formation of nitriles at the expense of isothiocyanates upon glucosinolate hydrolysis with unknown consequences for microbial colonisation of roots and rhizosphere.

Investigation on the physico-chemical properties of soil and mineralization of three selected tropical tree leaf litter.

Plant leaf litter has a major role in the structure and function of soil ecosystems as it is associated with nutrient release and cycling. The present study is aimed to understand how well the decomposing leaf litter kept soil organic carbon and nitrogen levels stable during an incubation experiment that was carried out in a lab setting under controlled conditions and the results were compared to those from a natural plantation. In natural site soil samples, Anacardium.

Preparation and Characterization of Magnetite-Polyvinyl Alcohol Hybrid Nanoparticles (As-PVA-MNPs) Using Acanthophora spicifera Marine Algae Extract for Enhanced Antimicrobial Activity Against Pathogenic Microorganisms.

The present study focused on preparing and characterizing magnetite-polyvinyl alcohol (PVA) hybrid nanoparticles using Acanthophora spicifera marine algae extract as a reducing agent. Various analytical techniques, including UV-Visible spectrometry, Fourier-transform infrared (FTIR) analysis, energy-dispersive X-ray (EDX), scanning electron microscopy (SEM), and X-ray diffraction (XRD) analysis, were used to characterize the nanoparticles. The results showed the successful synthesis of nanoparticles with a characteristic color change and absorption peak at 400 nm in UV-Visible spectrometry.

Trajectory in biological metal-organic frameworks: Biosensing and sustainable strategies-perspectives and challenges.

The ligand attribute of biomolecules to form coordination bonds with metal ions led to the discovery of a novel class of materials called biomolecule-associated metal-organic frameworks (Bio-MOFs). These biomolecules coordinate in multiple ways and provide versatile applications. Far-spread bio-ligands include nucleobases, amino acids, peptides, cyclodextrins, saccharides, porphyrins/metalloporphyrin, proteins, etc.

Comprehensive review on recent production trends and applications of biochar for greener environment.

The suitability of biochar as a supplement for environmental restoration varies significantly based on the type of feedstocks used and the parameters of the pyrolysis process. This study comprehensively examines several aspects of biochar's potential benefits, its capacity to enhance crop yields, improve nutrient availability, support the co-composting, water restoration and enhance overall usage efficiency. The supporting mechanistic evidence for these claims is also evaluated.

Sustainable valorization approaches on crustacean wastes for the extraction of chitin, bioactive compounds and their applications - A review.

The unscientific disposal of the most abundant crustacean wastes, especially those derived from marine sources, affects both the economy and the environment. Strategic waste collection and management is the need of the hour. Sustainable valorization approaches have played a crucial role in solving those issues as well as generating wealth from waste.