Publications by authors named "Ravikumar Soumya"
Objectives: This study aimed to assess the effects of L-carnitine on oxidative stress in human erythrocytes during storage.
Background: Using antioxidants as components of blood storage solutions may combat the effects of storage-induced oxidative stress on erythrocytes.
Methods: Blood from male adults was stored at 4 °C for 55 days in citrate phosphate dextrose adenine solution, without L-carnitine (Control) and with L-carnitine as an additive (at concentrations of 10, 30 and 60 mM - Experiments).
Background/aim: Curcumin, a naturally occurring antioxidant, shows a wide variety of medicinal properties. The possibility of utilizing curcumin as an additive in storage solutions of blood has not been explored. The purpose of this study was to analyze the effect of curcumin on erythrocytes during storage.
View Article and Find Full Text PDFObjective: To understand the responses of A, B, and O blood groups to oxidative stress (OS) induced through storage.
Methods: A, B, and O blood units were obtained from the blood bank at KIMS Hospital, Bangalore, and stored for 35 days at 4°C in citrate phosphate dextrose adenine-1 solution. Every fifth day, hemoglobin (Hb) was assessed in whole blood and erythrocytes were isolated from each group.
Objective: The CUPRAC-BCS and antioxidant activity (AOA) assays have been developed as indirect methods to determine the total antioxidant capacity (TAC). We examined these assays as markers, in erythrocytes, under oxidative stress (induced by storage) and with antioxidants--vitamin C, L-carnitine, and curcumin.
Methods: Antioxidants were added to blood samples, stored and assayed for TAC and reactive oxygen species (ROS).