An effective strategy for development of docetaxel encapsulated gold nanoformulations for treatment of prostate cancer.

Nanoformulation based drug delivery is one of the most important research areas in the field of nanomedicine, which provides promising alternatives to the limitations of conventional chemotherapy. Nano drug delivery enables improved pharmacokinetic profile, bioavailability and therapeutic efficiency compared to the regular chemotherapeutic drugs. Herein, we have established a simple method for the synthesis of docetaxel (Dtx) encapsulated poly (ethylene glycol) (PEG) functionalized gold nanoparticles (AuNPs) for targeted drug delivery to prostate cancer.

Evaluation of cytotoxic activity of docetaxel loaded gold nanoparticles for lung cancer drug delivery.

The effective use of the gold nanoparticle (AuNPs) conjugated drugs for targeted drug delivery applications is one of the most promising research areas in the field of cancer. Herein, we aimed to establish a nano drug conjugated with docetaxel as a possible therapy option. Gold nanoparticles were synthesized by chemical reduction method.

Seed-free synthesis of 1D silver nanowires ink using clove oil (Syzygium Aromaticum) at room temperature.

Hypothesis: Silver nanowires (AgNWs) have been demonstrated to be a promising next generation conducting material and an alternative to the traditional electrode (ITO) because of its high conductivity, transparency and stability. Generally, AgNWs are synthesized by chemical method (mainly polyol reduction method) at high temperature in the presence of exotic seeds. The present work aims at the green approach for preparation and characterization of 1D AgNWs ink using clove oil (Syzygium Aromaticum) at room temperature.

Sputter-deposition of silver nanoparticles into ionic liquid as a sacrificial reservoir in antimicrobial organosilicate nanocomposite coatings.

We present a new approach for fabricating robust, regenerable antimicrobial coatings containing an ionic liquid (IL) phase incorporating silver nanoparticles (AgNPs) as a reservoir for Ag(0)/Ag(+) species within sol-gel-derived nanocomposite films integrating organosilicate nanoparticles. The IL serves as an ultralow volatility (vacuum-compatible) liquid target, allowing for the direct deposition and dispersion of a high-density AgNP "ionosol" following conventional sputtering techniques. Two like-anion ILs were investigated in this work: methyltrioctylammonium bis(trifluoromethylsulfonyl)imide, [N(8881)][Tf(2)N], and 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, [emim][Tf(2)N].

A metal dispersed sol-gel biocomposite amperometric glucose biosensor.

A new glucose biosensor has been fabricated by immobilizing glucose oxidase into a copper dispersed sol-gel derived ceramic-graphite composite. The copper in the biocomposite offers excellent electrocatalytic activity towards the reduction (at -0.2 V) as well as oxidation (at +0.

Determination of hydrogen peroxide based on a metal dispersed sol-gel derived ceramic-graphite composite electrode.

A new copper dispersed ceramic-graphite composite electrode was fabricated by the initial mixing of copper nitrate and (3-mercaptopropyl)trimethoxy silane (MPS) followed by stirring with graphite powder. The combination of the metal catalysis and the advantages of the ceramic composite favored the electrocatalytic reduction of hydrogen peroxide (H2O2) at a reduced overpotential of -0.2 V with good sensitivity, stability and reproducibility.