Operationalizing a Pandemic-Ready, Telemedicine-Enabled Drive-Through and Walk-In Coronavirus Disease Garage Care System as an Alternative Care Area: A Novel Approach in Pandemic Management.

Objective: Emergency departments face unforeseen surges in patients classified as low acuity during pandemics such as the coronavirus disease pandemic. Streamlining patient flow using telemedicine in an alternative care area can reduce crowding and promote physical distancing between patients and clinicians, thus limiting personal protective equipment use. This quality improvement project describes critical elements and processes in the operationalization of a telemedicine-enabled drive-through and walk-in garage care system to improve ED throughput and conserve personal protective equipment during 3 coronavirus disease surges in 2020.

Endophytic Microbiome Responses to Sulfur Availability in (L.).

Sulfur is an essential plant macronutrient, and its adequate supply allows an efficient root storage and sugar extractability in sugar beets (  L.). In this study, we investigated the effect of changes in sulfur availability on the endophytic community structure of sugar beets.

Effects of uniform vertical inflow perturbations on the performance of flapping wings.

Flapping wings have attracted significant interest for use in miniature unmanned flying vehicles. Although numerous studies have investigated the performance of flapping wings under quiescent conditions, effects of freestream disturbances on their performance remain under-explored. In this study, we experimentally investigated the effects of uniform vertical inflows on flapping wings using a Reynolds-scaled apparatus operating in water at Reynolds number ≈ 3600.

Chemistry, Pharmacology and Therapeutic Potential of Swertiamarin - A Promising Natural Lead for New Drug Discovery and Development.

Swertiamarin, a seco-iridoid glycoside, is mainly found in Blume () and exhibits therapeutic activities for various diseases. The present study aimed to provide a review of swertiamarin in terms of its phytochemistry, physicochemical properties, biosynthesis, pharmacology and therapeutic potential. Relevant literature was collected from several scientific databases, including PubMed, ScienceDirect, Scopus and Google Scholar, between 1990 and the present.

Functional prediction of de novo uni-genes from chicken transcriptomic data following infectious bursal disease virus at 3-days post-infection.

Background: Infectious bursal disease (IBD) is an economically very important issue to the poultry industry and it is one of the major threats to the nation's food security. The pathogen, a highly pathogenic strain of a very virulent IBD virus causes high mortality and immunosuppression in chickens. The importance of understanding the underlying genes that could combat this disease is now of global interest in order to control future outbreaks.

Heterotopic Ossification after Knee Surgery, Arthroscopy is Not an Exception!!!!

Introduction: Reconstruction of the anterior cruciate ligament (ACL) is a common procedure. Injury is the predisposing risk factor for developing heterotopic ossification(HO). We like to report a case of HO of the knee following arthroscopic ACL reconstruction.

Performance of passively pitching flapping wings in the presence of vertical inflows.

The successful implementation of passively pitching flapping wings strongly depends on their ability to operate efficiently in wind disturbances. In this study, we experimentally investigated the interaction between a uniform vertical inflow perturbation and a passive-pitching flapping wing using a Reynolds-scaled apparatus operating in water at Reynolds number ≈3600. A parametric study was performed by systematically varying the Cauchy number () of the wings from 0.

Visual and movement memories steer foraging bumblebees along habitual routes.

One persistent question in animal navigation is how animals follow habitual routes between their home and a food source. Our current understanding of insect navigation suggests an interplay between visual memories, collision avoidance and path integration, the continuous integration of distance and direction travelled. However, these behavioural modules have to be continuously updated with instantaneous visual information.

A Case Report on Parosteal Lipoma Stretching the Posterior Interosseous Nerve Without Causing Palsy.

Lipomas are benign soft tissue tumors that can be either superficial or deep. Superficial lipomas are mostly asymptomatic whereas deep-seated lipomas can occasionally cause symptoms if they grow adjacent to neurovascular structures. In this report, we present a case of parosteal lipoma of the right proximal forearm in a 47-year-old male, which was initially diagnosed as intramuscular lipoma stretching posterior interosseous nerve (PIN), with no neurological complaints during both preoperative and postoperative periods.

Optimizing Nondecomposable Data Dependent Regularizers via Lagrangian Reparameterization Offers Significant Performance and Efficiency Gains.

Data dependent regularization is known to benefit a wide variety of problems in machine learning. Often, these regularizers cannot be easily decomposed into a sum over a finite number of terms, e.g.

Comparative Proteomic Analysis Reveals Novel Biomarkers for Gastric Cancer in South Indian Tamil Population.

Background: Gastric Cancer (GC) remains a major global health problem due to a poor understanding of its progression at the molecular level and a lack of early detection or diagnosis. Early detection is highly crucial for improving prognosis. The incidence of GC is very high in countries, like India, due to the limitations among the established biomarkers for GC owing to poor sensitivity and specificity.

Harnessing the physicochemical properties of DNA as a multifunctional biomaterial for biomedical and other applications.

The biological purpose of DNA is to store, replicate, and convey genetic information in cells. Progress in molecular genetics have led to its widespread applications in gene editing, gene therapy, and forensic science. However, in addition to its role as a genetic material, DNA has also emerged as a nongenetic, generic material for diverse biomedical applications.

Proximal Migration of Pancreatic Duct Stent in Pancreas Divisum: Challenges in Retrieval and Review of the Literature.

Pancreas divisum is the most common congenital malformation of the pancreas. Sometimes it is considered an etiology when patients present with recurrent episodes of pancreatitis. Endoscopic retrograde pancreatography (ERP) with selective cannulation of the minor papilla with sphincterotomy and stent placement are performed in these patients.

An insight on 7- ketocholesterol mediated inflammation in atherosclerosis and potential therapeutics.

7-ketocholesterol, a toxic oxidative product of oxysterol is a causative agent of several diseases and disabilities concomitant to aging including cardiovascular diseases like atherosclerosis. Auto-oxidation of cholesterol esters present in low-density lipoprotein (LDL) deposits lead to the formation of oxidized LDL (Ox-LDL) along with its byproducts, namely 7KCh. It is predominantly found in atherosclerotic plaque and also found to be more atherogenic than cholesterol by being cytotoxic, interfering with cellular homeostasis.

Automated, multiparametric monitoring of respiratory biomarkers and vital signs in clinical and home settings for COVID-19 patients.

Capabilities in continuous monitoring of key physiological parameters of disease have never been more important than in the context of the global COVID-19 pandemic. Soft, skin-mounted electronics that incorporate high-bandwidth, miniaturized motion sensors enable digital, wireless measurements of mechanoacoustic (MA) signatures of both core vital signs (heart rate, respiratory rate, and temperature) and underexplored biomarkers (coughing count) with high fidelity and immunity to ambient noises. This paper summarizes an effort that integrates such MA sensors with a cloud data infrastructure and a set of analytics approaches based on digital filtering and convolutional neural networks for monitoring of COVID-19 infections in sick and healthy individuals in the hospital and the home.

Crop Fires and Cardiovascular Health - A Study from North India.

We examine the impact of exposure to biomass burning events (primarily crop burning) on the prevalence of hypertension in four North Indian states. We use data from the National Family Health Survey-IV for 2015-16 and employ a multivariate logistic and linear model to estimate the effect of exposure to biomass burning on the prevalence of hypertension and blood pressure, respectively. The adjusted odds ratio of hypertension among individuals living in areas with high intensity of biomass (HIB) burning (defined as exposure to 100 fire-events during the past 30 days) is 1.

Medical image analysis based on deep learning approach.

Medical imaging plays a significant role in different clinical applications such as medical procedures used for early detection, monitoring, diagnosis, and treatment evaluation of various medical conditions. Basicsof the principles and implementations of artificial neural networks and deep learning are essential for understanding medical image analysis in computer vision. Deep Learning Approach (DLA) in medical image analysis emerges as a fast-growing research field.

Novel Effects of Leonardite-Based Applications on Sugar Beet.

The present study aimed to explore the effects of foliar application of a leonardite-based product on sugar beet ( L.) plants grown in the field. The approach concerned the evaluation of the community compositional structure of plant endophytic bacteria through a metabarcoding approach, the expression level of a gene panel related to hormonal metabolism and signaling, and the main sugar beet productivity traits.

Quantification of rhizomania virus by automated RNA isolation and PCR based methods in sugar beet.

Unlabelled: Rhizomania is a grave disease affecting sugar beet ( L.). It is caused by the Beet Necrotic Yellow Vein Virus (BNYVV), an RNA virus transmitted by the plasmodiophorid vector .

Developmental Changes in the Association Between Cognitive Control and Anxiety.

Anxiety has been associated with reliance on reactive (stimulus-driven/reflexive) control strategies in response to conflict. However, this conclusion rests primarily on indirect evidence. Few studies utilize tasks that dissociate the use of reactive ('just in time') vs.

Managed aquifer recharge implementation criteria to achieve water sustainability.

Depletion of groundwater is accelerated due to an increase in water demand for applications in urbanized areas, agriculture sectors, and energy extraction, and dwindling surface water during changing climate. Managed aquifer recharge (MAR) is one of the several methods that can help achieve long-term water sustainability by increasing the natural recharge of groundwater reservoirs with water from non-traditional supplies such as excess surface water, stormwater, and treated wastewater. Despite the multiple benefits of MAR, the wide-scale implementation of MAR is lacking, partly because of challenges to select the location for MAR implementation and identify the MAR type based on site conditions and needs.

Challenging drug-resistant TB treatment journey for children, adolescents and their care-givers: A qualitative study.

Background: Childhood multidrug-resistant TB (MDR-TB) still affects around 25000 children every year across the globe. Though the treatment success rates for drug-resistant TB (DR-TB) in children are better than adults, children and adolescents face unique hurdles during DR-TB (MDR-TB, Pre-XDR TB and XDR-TB) treatment. This study aimed to understand the patients, guardians and healthcare providers' perspectives about DR-TB treatment journey of patients and caregivers.

A beyond Born-Oppenheimer treatment of CH radical cation for diabatic surfaces: Photoelectron spectra of its neutral analog using time-dependent discrete variable representation.

We employ theoretically "exact" and numerically "accurate" Beyond Born-Oppenheimer (BBO) treatment to construct diabatic potential energy surfaces (PESs) of the benzene radical cation (CH ) for the first time and explore the workability of the time-dependent discrete variable representation (TDDVR) method for carrying out dynamical calculations to evaluate the photoelectron (PE) spectra of its neutral analog. Ab initio adiabatic PESs and nonadiabatic coupling terms are computed over a series of pairwise normal modes, which exhibit rich nonadiabatic interactions starting from Jahn-Teller interactions and accidental conical intersections/seams to pseudo Jahn-Teller couplings. Once the electronic structure calculation is completed on the low-lying five doublet electronic states (X̃E, B̃E, and C̃A) of the cationic species, diabatization is carried out employing the adiabatic-to-diabatic transformation (ADT) equations for the five-state sub-Hilbert space to compute highly accurate ADT angles, and thereby, single-valued, smooth, symmetric, and continuous diabatic PESs and couplings are constructed.