Publications by authors named "Ravi Krishna Kanth"
Article Synopsis
- The study focuses on meningoencephalitis, which involves both meningitis and encephalitis, aiming to analyze the clinical features, lab tests, imaging results, and factors predicting outcomes in affected patients.
- Conducted from July 2021 to March 2023, it enrolled patients who met the case definitions for meningitis and encephalitis, tracking their mortality and health recovery over one and three months post-discharge.
- Out of 102 cases, various infectious and non-infectious causes were identified, with notable findings in cerebrospinal fluid analysis and imaging; particularly, high mortality rates were seen in fungal and rickettsial cases while patient recovery varied depending on the type of meningoencephalitis experienced
A 32-year old lady with AQP4-Antibody positive neuromyelitis optica developed a new-onset complex movement disorder after therapeutic plasma exchange, which was initially suspected to be hypocalcemic carpo-pedal spasm. However, when her bilateral, distal predominant, paroxysmal, stereotypic, wrist and finger flexor tonic contractions did not respond to serum calcium correction, other diagnoses were considered. The patient had a dramatic response to oral carbamazepine suggesting that the tonic spasms were likely a spinal movement disorder due to the primary demyelinating pathology.
View Article and Find Full Text PDFSensory ataxic polyneuropathy unmasking late-onset urea cycle defect.
Clin Neurol Neurosurg
May 2024
Article Synopsis
- A 63-year-old man with type 2 diabetes and a history of hepatic encephalopathy presented with lower limb weakness, sensory issues, and mood swings, alongside a family history of mental disorders.
- Nerve conduction studies revealed demyelinating polyradiculoneuropathy, while MRI indicated thickened cranial and lumbosacral nerves; he was initially treated for chronic inflammatory polyneuropathy.
- After developing encephalopathy and an elevated serum ammonia level, further tests pointed to ornithine transcarbamylase (OTC) deficiency, leading to successful treatment with hemodialysis and dietary changes.