Safety Assessment of UBSS-01 in Rats and Double-Blind Placebo-Controlled Study in Healthy Individuals.

is a common, harmless, and prevalent member of the oral microbiota in humans. In the present study, the safety of UBSS-01 was evaluated using in silico methods and preclinical and clinical studies. In an acute toxicity study, rats were administered with 5 g/kg (500 × 10 CFU) UBSS-01.

The rise in antimicrobial resistance: An obscure issue in COVID-19 treatment.

A saturated health care system with a lack of evidence-based antiviral medicine and ignorance of antimicrobial stewardship during pandemics has prompted clinicians to prescribe a broad-spectrum antibiotic more often. A prospective, cross-sectional study of COVID-infected patients was conducted to gain insight into antibiotic prescribing practices and their impact on antimicrobial resistance. The antibiotic susceptibility test was performed using the disc diffusion method.