Optimized dual-tree complex wavelet transform aided multimodal image fusion with adaptive weighted average fusion strategy.

Image fusion is generally utilized for retrieving significant data from a set of input images to provide useful informative data. Image fusion enhances the applicability and quality of data. Hence, the analysis of multimodal image fusion is a new to the research topic, which is designed by combining the images of multimodal into single image in order to preserveexact details.

Modeling the START transition in the budding yeast cell cycle.

Budding yeast, Saccharomyces cerevisiae, is widely used as a model organism to study the genetics underlying eukaryotic cellular processes and growth critical to cancer development, such as cell division and cell cycle progression. The budding yeast cell cycle is also one of the best-studied dynamical systems owing to its thoroughly resolved genetics. However, the dynamics underlying the crucial cell cycle decision point called the START transition, at which the cell commits to a new round of DNA replication and cell division, are under-studied.

The phage shock protein (PSP) envelope stress response: discovery of novel partners and evolutionary history.

Bacterial phage shock protein (PSP) systems stabilize the bacterial cell membrane and protect against envelope stress. These systems have been associated with virulence, but despite their critical roles, PSP components are not well characterized outside proteobacteria. Using comparative genomics and protein sequence-structure-function analyses, we systematically identified and analyzed PSP homologs, phyletic patterns, domain architectures, and gene neighborhoods.

A quantitative study on the impact of educational modules on the awareness of postural ergonomics among the dental clinical trainees of Jouf University: A North Saudi Arabian Cohort.

This research aimed to evaluate the difference between self-reported and actual work postures among dental clinical trainees and the effect of health education on their ergonomic postures. Bad postures induce fatigue, musculoskeletal pain, errors, a negative attitude, and job dissatisfaction. It is necessary to evaluate the awareness of posture ergonomics among clinical trainees as the bad postures captured during their learning years transform into habits that could affect future productivity.

Effect of Different Irrigant Activation Techniques on the Penetration of Calcium Hydroxide, an Intracanal Medicament: An In Vitro Study.

Background and objective The main goal of root canal treatment is to eliminate microorganisms from the canal and to prevent re-infection. To achieve these goals, instrumentation must be combined with adequate irrigation and the placement of intracanal medicament. This study aims to compare the effect of different irrigation activation techniques, i.

Extracellular matrix type 0: From ancient collagen lineage to a versatile product pipeline - JellaGel™.

Extracellular matrix type 0 is reported. The matrix is developed from a jellyfish collagen predating mammalian forms by over 0.5 billion years.

Multi-spectroscopic, thermodynamic and molecular simulation studies on binding of pyrroloquinoline quinone with DNA: coexistence of intercalation and groove binding modes.

The interaction between enzyme-like pyrroloquinoline quinone () and calf-thymus DNA (CT-DNA) has been investigated by means of multi-spectroscopic (UV-Vis, fluorescence and circular dichroism), isothermal titration calorimetric (ITC), viscometry and molecular docking and metadynamics simulation techniques. Absorption spectral data suggested the formation of a /CT-DNA complex, which quenched the fluorescence of the dynamic quenching process. The results of CD spectral studies coupled with viscosity measurements, competitive binding assays with Hoechst 33258 and ethidium bromide (EB), KI quenching experiments, gel electrophoresis and DNA melting studies indicated groove binding mode of interaction of with CT-DNA.

The glutathione import system satisfies the Staphylococcus aureus nutrient sulfur requirement and promotes interspecies competition.

Sulfur is an indispensable element for bacterial proliferation. Prior studies demonstrated that the human pathogen Staphylococcus aureus utilizes glutathione (GSH) as a source of nutrient sulfur; however, mechanisms of GSH acquisition are not defined. Here, we identify a five-gene locus comprising a putative ABC-transporter and predicted γ-glutamyl transpeptidase (ggt) that promotes S.

Survival rate and stability of surface-treated and non-surface-treated orthodontic mini-implants: a randomized clinical trial.

Objectives: This clinical trial was conducted to evaluate the stability and failure rate of surface-treated orthodontic mini-implants and determine whether they differ from those of non-surface-treated orthodontic mini-implants.

Trial Design: Randomized clinical trial with a split-mouth study design.

Setting: Department of Orthodontics, SRM Dental College, Chennai.

Prevalence of disability among the elderly people in an urban slum of Chennai - A cross-sectional study.

Background: Human population is ageing worldwide. Disabilities are common with ageing; but most of the studies focused on the medical model of disability. However, "disability and elderly" encompasses a larger spectrum of conditions and needs to be studied as a broader concept.

Text embedding techniques for efficient clustering of twitter data.

World wide web is abundant with various types of information such blogs, social media posts, news articles. With this type of magnitude of online content, there is a need to deeply understand the insights of it in order to make use of the information for practical applications such as event detection, polarity, sentiment analysis and so on. Natural Language Processing (NLP) is the study of such information which is used for text classification, sentiment analysis, clustering of similar text.

Amphibian-like Flexible Organic Crystal Optical Fibers for Underwater/Air Micro-Precision Lighting and Sensing.

Visible light guiding optical fibers with underwater operational capability are highly desired for subaquatic communication and sensing technologies. Herein, we present mechanically flexible, blue-violet fluorescent (4,4'-bis(2,6-di(1H-pyrazol-1-yl)pyridin-4-yl)biphenyl) (BPP) crystal waveguides with high-aspect ratio. These milli-meter-long BPP crystals guide light actively and passively in ambient and underwater conditions demonstrating their amphibian-like character.

Feedback in the β-catenin destruction complex imparts bistability and cellular memory.

Wnt ligands are considered classical morphogens, for which the strength of the cellular response is proportional to the concentration of the ligand. Herein, we show an emergent property of bistability arising from feedback among the Wnt destruction complex proteins that target the key transcriptional co-activator β-catenin for degradation. Using biochemical reconstitution, we identified positive feedback between the scaffold protein Axin and the kinase glycogen synthase kinase 3 (GSK3).

A Broadband, Multiplexed-Visible-Light-Transport in Composite Flexible-Organic-Crystal Waveguide.

We report the construction of an organic crystal multiplexer using three chemically and optically different acicular, flexible organic crystals for a broadband, visible light signal transportation. The mechanical integration of a highly flexible crystal waveguide of (Z)-2-(3,5-bis(trifluoromethyl)phenyl)-3-(7-methoxybenzo[c][1,2,5]thiadiazol-4-yl)acrylonitrile (BTD2CF ) displaying bright yellow (λ ) fluorescence with blue-emitting (λ ) BPP and cyan emitting (λ ) DBA crystals using AFM-tip provides a composite organic crystal multiplexer. The constructed hybrid single crystal multiplexer effectively transduces three optical signals (λ +λ +λ ) covering the 420-750 nm region as a composite output signal.

Novel internalin P homologs in .

() is a bacterial pathogen that causes listeriosis in immunocompromised individuals, particularly pregnant women. Several virulence factors support the intracellular lifecycle of and facilitate cell-to-cell spread, allowing it to occupy multiple niches within the host and cross-protective barriers, including the placenta. One family of virulence factors, internalins, contributes to pathogenicity by inducing specific uptake and conferring tissue tropism.

DciA Helicase Operators Exhibit Diversity across Bacterial Phyla.

A fundamental requirement for life is the replication of an organism's DNA. Studies in Escherichia coli and Bacillus subtilis have set the paradigm for DNA replication in bacteria. During replication initiation in E.

Ten simple rules to host an inclusive conference.

Conferences are spaces to meet and network within and across academic and technical fields, learn about new advances, and share our work. They can help define career paths and create long-lasting collaborations and opportunities. However, these opportunities are not equal for all.

Phage defence by deaminase-mediated depletion of deoxynucleotides in bacteria.

Vibrio cholerae biotype El Tor is perpetuating the longest cholera pandemic in recorded history. The genomic islands VSP-1 and VSP-2 distinguish El Tor from previous pandemic V. cholerae strains.

Orthokeratinized versus parakeratinized odontogenic keratocyst: Our institutional experience.

Introduction: The odontogenic keratocyst (OKC) is quite unique among odontogenic cysts in its specific histological features and in clinical characteristics. The OKC has two variants orthokeratinized odontogenic cyst (OOC) and parakeratinized odontogenic cyst (POC), and POC is considered to be more aggressive and has a high recurrence rate. Therefore, OKC has generated considerable controversy with regard to its true nature.

Adaptable Optical Microwaveguides From Mechanically Flexible Crystalline Materials.

Flexible organic crystals (elastic and plastic) are important materials for optical waveguides, tunable optoelectronic devices, and photonic integrated circuits. Here, we present highly elastic organic crystals of a Schiff base, 1-((E)-(2,5-dichlorophenylimino)methyl)naphthalen-2-ol (1), and an azine molecule, 2,4-dibromo-6-((E)-((E)-(2,6-dichlorobenzylidene)hydrazono)methyl)phenol (2). These microcrystals are highly flexible under external mechanical force, both in the macroscopic and the microscopic regimes.

Micromechanically-Powered Rolling Locomotion of a Twisted-Crystal Optical-Waveguide Cavity as a Mobile Light Polarization Rotor.

We demonstrate mechanically-powered rolling locomotion of a twisted-microcrystal optical-waveguide cavity on the substrate, rotating the output signal's linear-polarization. Self-assembly of (E)-2-bromo-6-(((4-methoxyphenyl)imino)methyl)-4-nitrophenol produces naturally twisted microcrystals. The strain between several intergrowing, orientationally mismatched nanocrystalline fibres dictates the pitch lengths of the twisted crystals.

Reconciling multiple connectivity scores for drug repurposing.

The basis of several recent methods for drug repurposing is the key principle that an efficacious drug will reverse the disease molecular 'signature' with minimal side effects. This principle was defined and popularized by the influential 'connectivity map' study in 2006 regarding reversal relationships between disease- and drug-induced gene expression profiles, quantified by a disease-drug 'connectivity score.' Over the past 15 years, several studies have proposed variations in calculating connectivity scores toward improving accuracy and robustness in light of massive growth in reference drug profiles.

S-layers: The Proteinaceous Multifunctional Armors of Gram-Positive Pathogens.

S-layers are self-assembled crystalline 2D lattices enclosing the cell envelopes of several bacteria and archaea. Despite their abundance, the landscape of S-layer structure and function remains a land of wonder. By virtue of their location, bacterial S-layers have been hypothesized to add structural stability to the cell envelope.

Switching Cytolytic Nanopores into Antimicrobial Fractal Ruptures by a Single Side Chain Mutation.

Disruption of cell membranes is a fundamental host defense response found in virtually all forms of life. The molecular mechanisms vary but generally lead to energetically favored circular nanopores. Here, we report an elaborate fractal rupture pattern induced by a single side-chain mutation in ultrashort (8-11-mers) helical peptides, which otherwise form transmembrane pores.

Molecular organization of cytokinesis node predicts the constriction rate of the contractile ring.

The molecular organization of cytokinesis proteins governs contractile ring function. We used single molecule localization microscopy in live cells to elucidate the molecular organization of cytokinesis proteins and relate it to the constriction rate of the contractile ring. Wild-type fission yeast cells assemble contractile rings by the coalescence of cortical proteins complexes called nodes whereas cells without Anillin/Mid1p (Δmid1) lack visible nodes yet assemble contractile rings competent for constriction from the looping of strands.