Inherited 2q23.1 microdeletions involving the locus.

Background: Microdeletions of 2q23.1 disrupting and loss of function mutations of cause Associated Neurodevelopmental disorders (MAND). Nearly all reported patients have been isolated cases of de novo origin.

Sciatica: An Extremely Rare Complication of the Perianal Abscess.

Background: Sciatica has been classically described as pain in the back and hip with radiation in the leg along the distribution of the sciatic nerve, secondary to compression or irritation of the sciatic nerve. Spinal abnormality being the most common etiology, is one of the most common indications for MRI of the lumbosacral spine. Here we describe imaging findings secondary to a supralevator perianal abscess causing irritation of the sciatic nerve, which was diagnosed on MRI of the lumbosacral spine.