Modified oral metronidazole desensitization protocol.

The Center for Disease Control guidelines recommend desensitization to metronidazole in patients with trichomoniasis and hypersensitivity to metronidazole. There is only one published oral metronidazole desensitization protocol. The purpose of this study was to design a new, more gradual oral desensitization protocol to decrease systemic reactions that may occur when using the previously published protocol.

Utility of routine laboratory testing in management of chronic urticaria/angioedema.

Background: Laboratory tests are routinely ordered to identify or rule out a cause in patients with chronic urticaria/angioedema (CUA). The results of these tests are usually within normal limits or unremarkable.

Objective: To investigate the proportion of abnormal test results in patients with CUA leading to a change in management and in outcomes of care.