Publications by authors named "Raushan Zh Karabaeva"
Hypertension, a multifaceted cardiovascular disorder influenced by genetic, epigenetic, and environmental factors, poses a significant risk for the development of coronary artery disease (CAD) in individuals with type 2 diabetes mellitus (T2DM). Epigenetic alterations, particularly in histone modifications, DNA methylation, and microRNAs, play a pivotal role in unraveling the complex molecular underpinnings of blood pressure regulation. This review emphasizes the crucial interplay between epigenetic attributes and hypertension, shedding light on the prominence of DNA methylation, both globally and at the gene-specific level, in essential hypertension.
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- * A bibliometric analysis using VOSviewer software identified key genes and microRNAs associated with AH, revealing important roles these molecules play in the condition's development.
- * The study highlights specific microRNAs (like miR-7110-5p and miR-328-3p) that show strong binding to target genes, suggesting their potential as diagnostic and therapeutic tools for AH in the future.