Chemotherapy-associated steatohepatitis induced by irinotecan: a novel animal model.

Purpose: Nonalcoholic steatohepatitis (NASH) has been associated with irinotecan (IRI)-based cancer chemotherapy regimens. The purpose of this study was to propose and test a consistent model of IRI-induced NASH, filling a gap in the medical literature.

Methods: Swiss male mice were distributed in groups (n = 8) and injected with saline (5 mL/kg, i.

Blood pressure measurement in different outpatient clinics.

The objective of this study is to investigate how blood pressure is measured in different outpatient clinics. This is a retrospective study performed with 1,000 patients, randomly selected among patients followed in different outpatient clinics in Fortaleza, Brazil. Among the 1,000 patients, 962 had available records.