Anticancer Effects of Ethanolic Extracts of Leaves on Human Oral Squamous Carcinoma Cell Lines: An Study.

Cancer is a disease resulting from the disruption of cell cycle regulation, leading to the abnormal and unchecked proliferation of cells. Medicinal plants are rich in various bioactive phytochemicals or nutritional compounds. The aim is to determine the cytotoxic and genotoxic effects of ethanolic extracts of leaves on human oral cancer cell lines.

Assessment of Oxidant-Antioxidant Status and Stress Factor in Recurrent Aphthous Stomatitis Patients: Case Control Study.

Introduction: Despite its vast occurrence, the aetiology of Recurrent Aphthous Stomatitis (RAS) still remains unknown and its aetiology is multifactorial. The factors believed to be associated with the aetiology of RAS, may disturb the equilibrium of oxidant-antioxidant status of the organism and may accelerate the formation of free radicals, resulting in Oxidative Stress (OS). Psychological stress is believed to act as a triggering factor or modifying factor for RAS.

Prevalence of the developmental defects of the enamel in children aged 12-15 years in Kollam district.

Aim And Objectives: To determine the prevalence of developmental defects of enamel in children aged 12-15 years in Kollam district and to examine the etiological factors associated with the developmental defects of the enamel (DDE).

Materials And Methods: A total of 2,500 children from 10 urban and 10 rural schools were examined using modified DDE criteria for recording enamel defects. Ten index permanent teeth were screened for the DDE.

Comparative cytomorphometric analysis of oral mucosal cells in normal, tobacco users, oral leukoplakia and oral squamous cell carcinoma.

Background: Squamous cell carcinoma (SCC) is the third most common cause of oral morbidity in India despite the numerous advances made in the treatment protocol.

Aim: To compare the cytomorphometric changes of oral mucosal cells in normal subjects (Group I) with that of tobacco users without any lesion (Group II), tobacco users with oral leukoplakia (Group III), and tobacco users with oral SCC (Group IV) through a semi-automated image analysis system.

Materials And Methods: Oral mucosal cells collected from study subjects (n = 100) stained using rapid Papanicolaou stain.

Estimation of Salivary Glucose and Glycogen Content in Exfoliated Buccal Mucosal Cells of Patients with Type II Diabetes Mellitus.

Background: Diabetes mellitus is a common metabolic disorder which shows an increasing incidence worldwide. Constant monitoring of blood glucose in diabetic patient is required which involves painful invasive techniques. Saliva is gaining acceptance as diagnostic tool for various systemic diseases which can be collected noninvasively and by individuals with limited training.

Idiopathic orofacial granulomatosis with varied clinical presentation.

Orofacial granulomatosis is a granulomatous disease of orofacial region, which can occur for a variety of reasons. The clinical features are highly variable and sometimes so insidious that signs and symptoms are not frequently severe to cause alarm. The lips are most commonly involved with persistent/recurrent swelling.

Gorham's Disease of the Mandible.

Gorham's disease is a rare condition characterized by progressive osteolysis of bone with ultimate total disappearance of bone. The aetiology is undetermined. It may affect any bone of the body, although there is predilection for the pelvis, humerus, axial skeleton, and mandible.

Osteoradionecrosis of mandible: Case report with review of literature.

Osteoradionecrosis (ORN) of the jaws, particularly of the mandible, is a long-term and serious complication of therapeutic radiotherapy for head and neck cancer. The mandible is affected more commonly than any other bones of the head and neck region. The incidence of ORN of mandible is reported to be between 2% and 22%.

Dyskeratosis congenita: a report of two cases.

Oral manifestations play an important role in the diagnosis of many systemic conditions. Dyskeratosis congenita (DC) is a rare genodermatosis which exhibits oral leukoplakia, nail dystrophy, and reticular skin pigmentations as its primary features. DC has increased risk of developing constitutional anemias and malignancies and early diagnosis enables the patient to be monitored and proper interventional therapy to be instituted.

Primary mucosal melanoma: report of two cases.

Primary mucosal malignant melanoma is of unusual occurrence and poor prognosis. We report two cases of primary mucosal melanoma, one in a 70-year-old male in the palate and the other in a 73-year-old female in the maxillary sinus. Early diagnosis and proper clinical and cytologic evaluation is necessary to institute therapeutic intervention.