Identification of the best plant ratios for a polyherbal tea mix to obtain optimum antioxidant, antidiabetic, and β-glucuronidase inhibition activities.

Background: The influence of plant types and their ratios on the effectiveness of polyherbal formulations is a crucial yet underexplored area of research.

Objectives: This study aimed to identify the optimal ratios of Phylanthus debilis (PW), Osbeckia octrandra (HB), and Artrocarpus heterophyllus (WR) leaf powders for a polyherbal tea to achieve the best functional properties.

Material And Methods: A three-level factorial design was used to examine the combined effect of three independent variables (PW, WR, and HB) on antioxidant, antidiabetic, and β-glucuronidase inhibitory activities.

Long-term health manifestations of hump-nosed pit viper (Genus: ) bites.

Introduction: The hump-nosed pit viper (Genus: ) is a highly medically significant snake in Sri Lanka, responsible for the majority of venomous snakebites (22-77%). They are found throughout Sri Lanka and the Western Ghats region of India. The venom can lead to two types of effects: acute and long-term.

Epidemiology and clinical features of Hypnale nepa (hump-nosed pit viper) envenoming in Sri Lanka.

Sri Lanka homes 3 species of hump-nosed pit vipers including Hypnale Hypnale, H. zara and H. nepa from which, latter 2 are endemic to the country.

Cat-eyed snake (Genus: Boiga) bites in Sri Lanka: First authentic case series.

Cat snakes (Genus: Boiga) are considered to be of lesser medical important in Sri Lanka, as their bites are known to cause only mild local effects such as local pain and swelling at the site of the bite. Five species of cat snakes are found in Sri Lanka, of which three are endemic. They are widely distributed all over the country.

Epidemiological and clinical features of hump-nosed pit viper (Hypnale hypnale and Hypnale zara) envenoming in children.

Background: Bites by the hump-nosed pit vipers (HNPV) of the genus Hypnale are the commonest type of venomous snakebites in Sri Lanka. Their bites frequently cause local effects while rarely causing systemic envenoming, that may include acute kidney injury and coagulopathy. There are 3 species of genus Hypnale including H.

Therapeutic Plasma Exchange for Venom-Induced Thrombotic Microangiopathy Following Hump-Nosed Pit Viper (Genus: Hypnale) Bites: A Prospective Observational Study.

Introduction: -Thrombotic microangiopathy (TMA), which is the triad of acute kidney injury (AKI), microangiopathic hemolytic anemia (MAHA), and thrombocytopenia, is a rare complication of snakebites, and in Sri Lanka, it is commonly seen with hump-nosed pit viper (HNPV) bites.

Methods: -We conducted a prospective observational study of patients with AKI caused by HNPV bites in Teaching Hospital, Ratnapura, Sri Lanka for 6 y, commencing in June 2015. Some patients with TMA underwent therapeutic plasma exchange (TPE) and some did not.

Seat belt syndrome is caused by a different mechanism: A case report.

Introduction And Importance: Seat belt syndrome is associated with multiple visceral injuries and vertebral burst fractures. Small Intestinal perforations are seen in 5-15 % of blunt abdominal trauma. In our case, we will report a case that presented small intestinal perforation and thoracic vertebral fracture caused by a different mechanism.

Acute Myocardial Infarction After Russell's Viper (Daboia russelii) Bite.

Russell's viper (Daboia russelii) is a deadly venomous snake that causes most snakebite deaths in Sri Lanka. It is widely distributed all over the country, and it commonly causes venom-induced consumption coagulopathy and neuroparalysis. Cardiotoxic manifestations after Russell's viper bites are rare.

Rare association of traumatic diaphragmatic hernia with spinal cord injury: A case report.

Introduction And Importance: The traumatic diaphragmatic hernia could be missed in the background of spinal fractures due to neurological weakness. We report the first case of the management of thoracolumbar fracture-dislocation associated with diaphragmatic injury.

Presentation Of Case: 53-year-old male transferred from local hospital following fallen from a motorbike on the 4th day after the injury.

Purpura fulminans following hump-nosed pit viper (Hypnale hypnale) envenoming: A rare complication of snakebites.

Hump-nosed pit vipers of the genus Hypnale are highly venomous and reputed for the commonest venomous snakebites in Sri Lanka. They frequently cause local manifestations and less commonly cause systemic effects such as acute kidney injury and coagulopathy. There is no antivenom currently available in Sri Lanka for their envenoming.

Clinico-epidemiology of Hypnale zara (hump-nosed pit viper) envenoming in Sri Lanka.

Background: Hump-nosed vipers of the genus Hypnale are the most common cause of venomous snakebites in Sri Lanka. The genus includes three species: Hypnale hypnale, Hypnale zara and Hypnale nepa. Of them, H.

The effect of chemical exudates of three larvivorous fish species on oviposition preference of Aedes aegypti and Aedes albopictus (Diptera: Culicidae).

Mosquito species Aedes aegypti and Aedes albopictus are vectors of dengue worldwide. Mosquito vector control through maintaining larvivorous fish in water bodies is generally suggested, however, its underlying role towards oviposition preference of these dengue vectors is unknown in the Sri Lankan context. The current study investigated the effect of chemical exudates from larvivorous fish species Poecilia reticulata, Rasbora daniconius and Applocheilus dayi on the oviposition preference of Aedes mosquitoes.

Consumer perception and sensory profile of probiotic yogurt with added sugar and reduced milk fat.

The objective of this study was to determine the effect of different milk fat (MF, 0%, 1.5%, 3.3% (w/w)) or added sugar (AS, 0%, 3.

Acute neuromuscular paralysis, rhabdomyolysis and long lasting neurological deficits in Ceylon krait () bites: Two authentic cases from a serpentarium in Sri Lanka.

The Ceylon krait () is a highly venomous elapid snake endemic to Sri Lanka. Its bites are rare and only seven reports are found in the literature. Therefore, the clinical manifestations and natural history of envenoming of Ceylon krait are not well studied yet.

An efficient and high-yielding method for extraction and purification of linamarin from Cassava; biological evaluation.

During the last three decades, studies of linamarin extracted from cassava have received increased attention due to the presence of high cyanogenic compounds in these extracts. The methods that are utilized to isolate linamarin are either tedious or use acidic conditions resulting in poor yields. In this study, a novel cryocooled method of extraction has been developed to isolate linamarin from Cassava root peel.

Systemic bleeding including pulmonary haemorrhage following hump-nosed pit viper (Hypnale hypnale) envenoming: A case report from Sri Lanka.

Out of seven venomous land snake species of Sri Lanka, hump-nosed pit viper (Hypnale spp.) causes the commonest venomous snakebites. It is widely distributed all over the country except in the peninsula of Jaffna.

Kidney injury following envenoming by hump-nosed pit viper (Genus: Hypnale) in Sri Lanka: proven and probable cases.

Background: Hump-nosed pit vipers (Hypnale hypnale) are highly venomous snakes found in Sri Lanka and the Western Ghats region of India. They are the most common cause of venomous snakebites in Sri Lanka, mainly causing local envenoming leading to pain, swelling and necrosis. Systemic envenoming causing acute kidney injury and coagulopathy are more commonly recognized following their bites.

Clinical study on the effect of decoction of Pavetta indica Linn. in treatment of Purishaja Krimi with special reference to Enterobius vermicularis infestation.

Pavetta indica Linn. (Family: Rubiaceae; Sanskrit name: Papata) is 2-5 m tall, shrub or small tree with opposite branches and grows in the Asia - Pacific region including Sri Lanka. Purishaja Krimi is one of the worm infestations described in Ayurveda.

Efficacy of Sri Lankan Traditional Decoction of Katuwelbatu Deduru Katukadi in treatment of Kaphaja Shira Shula (Chronic Sinusitis).

Kaphaja Shira Shula is one of the Shiro Roga. Chronic sinusitis is inflammation of the sinuses behind the forehead, cheeks, and eyes, which continues for a long time or keeps recurring. Kaphaja Shira Shula can be correlated with Chronic Sinusitis.