Acta Crystallogr E Crystallogr Commun
September 2024
The title compound, (CHNO)[CuCl(CHNO)]·2HO, was prepared by reacting Cu acetate dihydrate, solid 8-hy-droxy-quinoline (8-HQ), and solid pyridine-2,6-di-carb-oxy-lic acid (Hpydc), in a 1:1:1 molar ratio, in an aqueous solution of dilute hydro-chloric acid. The Cu atom exhibits a distorted CuONCl octa-hedral geometry, coordinating two oxygen atoms and one nitro-gen atom from the tridentate Hpydc ligand and three chloride atoms; the nitro-gen atom and one chloride atom occupy the axial positions with Cu-N and Cu-Cl bond lengths of 2.011 (2) Å and 2.
View Article and Find Full Text PDFIn the title salt [systematic name: 4-(3-carb-oxy-1-ethyl-6-fluoro-4-oxo-1,4-di-hydro-quin-olin-7-yl)piperazin-1-ium nitrate], CHFNO ·NO , proton transfer from nitric acid to the N atom of the piperazine ring of norfloxacin has occurred to form a mol-ecular salt. In the extended structure, N-H⋯O hydrogen bonds link alternating cations and anions into [100] chains, which are reinforced by aromatic π-π stacking inter-actions between the quinoline moieties of the norfloxacinium cations.
View Article and Find Full Text PDFThe reaction of ethane-1,2-di-amine (en, CHN), the sodium salt of naphthalene-1,5-di-sulfonic acid (HNDS, CHOS), and nickel sulfate in an aqueous solution resulted in the formation of the title salt, [Ni(CHN)(HO)](CHOS)·2HO or [Ni(en)(HO)](NDS)·2HO. In the asymmetric unit, one half of an [Ni(en)(HO)] cation and one half of an NDS anion, and one water mol-ecule of crystallization are present. The Ni cation in the complex is positioned on a twofold rotation axis and exhibits a slight tetra-gonal distortion of the -NiON octa-hedron, with an Ni-N bond length of 2.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
March 2021
Objective: To determine clinical and social indicators in in-patients with schizophrenia depending on their participation in psychiatric rehabilitation.
Material And Methods: One hundred in-patients were randomly assigned to receive either rehabilitation along with the standard pharmacological treatment or standard pharmacological treatment alone. Thirty-five patients from the main group and 39 patients from control group completed three-month participation in the study.
Objective: To compare functional outcomes of various rectal reconstruction after total mesorectal excision.
Material And Methods: A prospective randomized trial included 90 patients with mid-to-low rectal carcinoma who underwent total mesorectal excision.
Results: There were 22 patients after J-pouch surgery, 30 patients with side-to-end anastomoses and 38 patients with end-to-end anastomoses.
Alburnoides holciki was described from the Hari River basin, which was the only basin it was known from. Populations from the Amu Darya basin were previously recognized as A. eichwaldii or Alburnoides sp.
View Article and Find Full Text PDFAim: To compare short-term outcomes after transanal total mesorectumectomy (Ta-TME) and laparoscopic (Lap-TME) procedure in 'difficult' patients.
Material And Methods: Prospective nonrandomized trial included patients with confirmed middle-/low rectum adenocarcinoma T1-4aN0-2M0 for the period November 2013 - September 2016. We identified 20 out of 55 in TA-TME and 14 out of 54 patients in Lap-TME group as those of 'difficult' subgroup: male, BMI ≥25 кг/м, previous chemoradiotherapy (CRT).
Zh Nevrol Psikhiatr Im S S Korsakova
May 2019
Aim: To determine the factors that shape attitudes towards people with severe mental disorders as well as to establish correlations between these factors and socio-demographic variables.
Material And Methods: Cross-sectional study was conducted among 1000 respondents in five regions of the country. The questionnaire included different aspects concerning the relation of society towards people with mental disorders.
Khirurgiia (Mosk)
December 2017
Purpose: Complete mesocolic excision (CME) appears to be a relatively new concept for colon cancer. The purpose is to evaluate the results of CME with high vascular ligation (D3 lymph node dissection) for right colon cancer. The presented study identifies possible risks and advantages of the proposed method, as well as the role of the laparoscopic approach.
View Article and Find Full Text PDFPurpose: The goals of this study were to assess safety and efficacy of triplet chemoradiotherapy (CRT) with paclitaxel for squamous cell anal carcinoma (SCAC).
Methods: Patients with stage I-IIIB SCAC were enrolled and received 52-58 Gy intensity-modulated radiotherapy (IMRT) (with dose based on the T stage) in consecutive daily 1.8-2.
Aim: To present early and remote surgical outcomes in patients with locally-advanced right-sided colonic cancer, invasion of pancreatic head and/or duodenal wall.
Material And Methods: Early and remote surgical outcomes were analyzed in 27 patients who underwent gastropancreatoduodenectomy combined with right-sided hemicolectomy (ileotransversostomy extirpation) for locally-advanced right-sided colonic cancer.
Results: Mean time of surgery was 300 (240-460) minutes, intraoperative blood loss - 2000 (500-7200) ml.
Aim: To describe current methods of surgical treatment of rare form of recurrent rectal cancer with sacral invasion.
Material And Methods: The article presents the methodology for the treatment of patients with recurrent colorectal cancer and sacral invasion using preoperative chemoradiotherapy followed by high-tech surgery of recurrent tumor removal with sacral resection at various levels (including high intersection at S1 level).
Conclusion: It was concluded that chemoradiotherapy is indicated in patients with recurrent colorectal cancer if it was not made at the first stage of treatment.
Purpose: The aim of this study was to investigate the feasibility of short-course radiotherapy with oral capecitabine, hyperthermia and delayed surgery for neoadjuvant treatment of rectal cancer.
Methods: Patients with clinically staged T2-3N0-2M0 primary rectal cancer were included. All patients received short-course 25 Gy in 5 Gy fractions radiotherapy with capecitabine, local hyperthermia and metronidazole.
Aim: To evaluate and compare intraoperative features, early surgical outcomes, quality of excised specimen after laparoscopic and transanal total mesorectal excision (LA-TME and TA-TME).
Material And Methods: Prospective randomized study included 45 patients with confirmed rectal adenocarcinoma (cT2-4N0-2M0) since October 2013. LA-TME and TA-TME groups consisted of 23 and 22 patients respectively.
Background: Transanal total mesorectal excision (taTME) has potential benefits of better visual control, especially in male patients with a high body mass index and low rectal cancer. However, this method has not yet been validated in clinical trials. The aim of this study was to compare the short-term outcomes of transanal and laparoscopic (lap) TME.
View Article and Find Full Text PDFDuring recent decades radiotherapy is the basis, on which it is built a medical complex that is the first-line treatment of patients with squamous cell carcinoma of the anal canal. An increase of overall and disease-free survival and quality of life of patients with squamous cell carcinoma of the anal canal at the present stage of development of a comprehensive medical treatment is largely due to the improvement of technical equipment of radiotherapy departments of oncology clinics. The use of modem linear electron accelerators and systems of computer dosimetric planning to create a 3D program of isodose distribution, diagnostic devices (computed tomography and magnetic resonance imaging) as well as a number of other conditions permit accurate summarizing of proposed dose, reducing of absorbed dose to critical structures, diminishing unplanned interruptions in chemoradiotherapy course by means of modern technologies of conformal radiotherapy (3D CRT, IMRT, VMAT).
View Article and Find Full Text PDFThe article discusses the possibility of neoadjuvant chemotherapy in colon cancer patients and rectal cancer patients without the additional use of radiation therapy. The possible risks and benefits of such approach are analyzed and the data of available clinical studies are provided.
View Article and Find Full Text PDFVestn Rentgenol Radiol
April 2012
Despite the international experience enriched in the number of observations of combination treatment in patients with rectal cancer, many issues remain to be the subject-matter of the discussion. This also applies to the estimation of the value of tumor regression after neoadjuvant chemoradiation therapy in order to develop indications for sphincter-sparing operations depending on the site of a tumor in the organ and their impact on long-term treatment results. The authors have gained experience with combination treatment in 157 patients with rectal cancer (T2-4 N0-2 M0) receiving neoadjuvant chemoradiation therapy in a cumulative radiation dose of 39.
View Article and Find Full Text PDFThe total of 296 T3-4NO-2 Federal Coloproctology Science Center colon cancer patients received treatment since 2004 to 2011, 165 patients (main group) also received treatment (pre- and postoperative irradiation, surgery, adjuvant chemotherapy) in P.A.Herzen State Clinical Research Center for Oncology.
View Article and Find Full Text PDFAn analysis of complex treatment of 154 patients with T2-4N0-2 stage rectal cancer is presented who were given preoperative chemoradiotherapy in regimen of dynamic functioning with total focal dose 39.5 Gy (71 patients of the first group) and 47 Gy (83 patients of the second group) using 5-fluororacil and cisplatin. A multivariant analysis has demonstrated a reliably increased frequency of total and close to total regressions of rectal cancer (1-2 stage by Mandard) in the second group as compared with reduced duration of the operative intervention the 1st group (43.
View Article and Find Full Text PDFComplex treatment included preoperative radiochemotherapy (fractionated TTD of 47 Gy), 5-FU 2.75-3.5 g, cisplatin 90 mg, surgery and postoperative adjuvant chemotherapy (XELOX).
View Article and Find Full Text PDFThe paper reviews the use of complex intensive care in 24 patients with poisonous snake bites, aged 12 to 63 years. Complex intensive care comprised conservative and surgical methods of therapy, including extracorporeal detoxicating techniques (hemosorption and plasmapheresis). All the patients have been discharged on recovery.
View Article and Find Full Text PDFAnesteziol Reanimatol
September 1991
14 hemosorption (HS) procedures have been performed in 6 patients after snake bites. The patients recovered after a few HS sessions. However small our experience is, it indicates high efficacy of HS in combination with other intensive care techniques in patients with snake bites and severe intoxication.
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