Publications by authors named "Rastard Naftari"
PLoS Comput Biol
January 2022
Article Synopsis
- Genome-wide association studies often struggle with imputation of untyped genetic variants in underrepresented populations, leading to suboptimal results.
- By sequencing full genomes of a small group from these populations, researchers aim to identify specific genetic markers (tag SNPs) to improve imputation accuracy.
- Using a cohort from Tanzania, the study shows that adding these tailored tag SNPs enhances imputation accuracy compared to the existing genotyping arrays, validating this approach.
