Publications by authors named "Rasmussen P"

Wastewater treatment plant (WWTP) workers are exposed to bioaerosols containing bacteria, fungi, and endotoxin, potentially posing health risks to workers. This study quantified personal exposure levels to airborne bacteria and fungi, endotoxin, and dust among 44 workers during two seasons at four WWTPs. Associations between the exposure measurements and serum levels of biomarkers CRP, SAA, and CC16 were also assessed.

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Currently, there are limited therapeutic options for patients with non-active secondary progressive multiple sclerosis. Therefore, real-world studies have investigated differences between patients with relapsing-remitting multiple sclerosis, non-active secondary progressive multiple sclerosis and active secondary progressive multiple sclerosis. Here, we explore patterns and predictors of transitioning between these phenotypes.

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People with intellectual disabilities (IDs) face health issues and barriers to physical activity. Health promotion programmes targeting this group are often short-term. Few programmes have been designed for people with IDs who live in supported housing staffed by social care workers (SCWs).

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Background: Moyamoya disease (MMD) is a rare cerebrovascular disorder marked by internal carotid artery narrowing, collateral neovascularization, and symptomatic cerebral ischemia. Select patients can benefit from direct bypass (superficial temporal artery [STA]-proximal middle [MCA] bypass) by restoring blood flow to hypoperfused territories. Symptomatic contralateral stroke (CS) following STA-MCA bypass is a devastating, poorly understood complication.

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Introduction: Anatomic factors that predict outcomes following basal ganglia intracranial hemorrhage (bgICH) evacuation are poorly understood. Given the compact neuroanatomic organization of the basal ganglia, we hypothesized that bgICH spatial representation could predict postoperative functional outcomes.

Methods: Patients undergoing minimally invasive surgical bgICH evacuation between 2013 and 2024 at one center were retrospectively reviewed.

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Article Synopsis
  • Teriflunomide, a medication for multiple sclerosis (MS), is linked to a higher risk of developing hypertension compared to another MS treatment, dimethyl fumarate.
  • A study involving nearly 5,000 adult patients over 10 years showed that hypertension events occurred significantly more in those on teriflunomide (40.6 per 1000 person-years) than in those on dimethyl fumarate (13.1 per 1000 person-years).
  • The findings indicate that patients on teriflunomide are 2.8 times more likely to develop hypertension, with a concerning "number needed to harm" of 16 at 3 years and 9 at 5 years.
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Objectives: This study aims to investigate (1) the microbial community composition by work characteristics and (2) the association between microbial genera level and inflammatory markers among recycling workers.

Methods: In this cross-sectional study, inhalable dust was collected with personal samplers from 49 production (86 samples) and 10 administrative workers (15 samples). Four groups of micro-organisms were identified down to species-level (aerobic and anaerobic bacteria, and fungi grown at 25°C and 37°C).

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  • The study focuses on the growing elderly population with atrial fibrillation (AF) and examines the effectiveness of AF ablation as a treatment for this group.
  • It analyzes data from Danish administrative records from 2001 to 2020, showing a significant increase in AF ablation procedures among the elderly, especially those aged 75 and older.
  • Results indicate a decrease in major adverse cardiovascular events (MACE) over time and that age is not a consistent predictor of AF-related complications or the need for further treatment.
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In lowlanders, high altitude (HA) acclimatization induces hemoconcentration by reducing plasma volume (PV) and increasing total hemoglobin mass (Hb). Conversely, Tibetan highlanders living at HA are reported to have a similar hemoglobin concentration ([Hb]) as lowlanders near sea level, and we investigated whether this reflects alterations in the PV or the Hb response to HA. Baseline assessment of PV and Hb was performed by carbon monoxide rebreathing at low altitudes (∼1,400 m) in Sherpas (an ethnic group of Tibetans living in Nepal) and native lowlanders.

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Fast radio bursts (FRBs) are millisecond-duration events detected from beyond the Milky Way. FRB emission characteristics favour highly magnetized neutron stars, or magnetars, as the sources, as evidenced by FRB-like bursts from a galactic magnetar, and the star-forming nature of FRB host galaxies. However, the processes that produce FRB sources remain unknown.

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The thermal conductivity of glasses is well-known to be significantly harder to theoretically describe compared to crystalline materials. Because of this fact, the fundamental understanding of thermal conductivity in glasses remain extremely poor when moving beyond the case of simple glasses, e.g.

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  • Inpatient rehabilitation improves health-related quality of life (HRQOL) for multiple sclerosis (MS) patients, but the benefits often lessen after returning home, prompting a study on monthly telecoaching to sustain improvements.
  • A one-year study compared two telecoaching methods (telephone and web-based) to see if they could help maintain HRQOL post-discharge, using a neuropsychological group and a physical group for analysis.
  • Results showed that the neuropsychological group experienced long-term HRQOL benefits from telecoaching, particularly with one-on-one phone support, while the physical group did not see any significant improvement.
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  • The rebuttal by Mills et al. (2024) defends the statistical methods used in the Randomised Badger Culling Trial (RBCT), particularly the choice of count over rate for assessing bovine tuberculosis herd incidence.
  • * The authors argue that previous analyses overfit data and incorrectly apply Bayesian methods, prioritizing model fit over practical predictive power in a small dataset context.
  • * Ultimately, the RBCT's findings on the impact of badger culling on bovine tuberculosis incidence are deemed unconvincing, with modern veterinary insights suggesting the original conclusions still stand but require a nuanced understanding.
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Congestive heart failure (CHF) and opioid use disorder (OUD) commonly coexist and are major contributors to high healthcare utilization in the United States. Medication assisted treatment (MAT; e.g.

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Recycling demands are increasing and new biowaste plants are established. The aim of this study is to obtain knowledge about occupational hygiene in biowaste pretreatment plants. At 6 plants, bioaerosol exposure, hand hygiene, and bioaerosol concentrations in work areas were investigated repeatedly.

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APOE-ɛ4 is a genetic risk factor for Alzheimer's disease (AD). AD is associated with reduced cerebral blood flow (CBF) and with microvascular changes that limit the transport of oxygen from blood into brain tissue: reduced microvascular cerebral blood volume and high relative transit time heterogeneity (RTH). Healthy APOE-ɛ4 carriers reveal brain regions with CBF compared with carriers of the common ɛ3 allele.

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This study aimed to assess the role of tourism in the spread of human immunodeficiency virus (HIV) using Malaysian epidemiological data on HIV and acquired immunodeficiency syndrome (AIDS) incidence from 1986 to 2004. A population-level mathematical model was developed with the following compartments: the population susceptible to HIV infection, the clinically confirmed HIV-positive population, the population diagnosed with AIDS, and the tourist population. Additionally, newborns infected with HIV were considered.

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Aims: Atrial fibrillation (AF) is a common arrhythmia associated with reduced quality of life that can lead to serious complications such as stroke and heart failure. Ablation is a safe and effective treatment for AF but is not offered equally to all patients. The aim of this study is to identify demographic groups more or less likely to undergo AF ablation.

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Introduction: Disturbances in microvascular flow dynamics are hypothesized to precede the symptomatic phase of Alzheimer's disease (AD). However, evidence in presymptomatic AD remains elusive, underscoring the need for therapies targeting these early vascular changes.

Methods: We employed a multimodal approach, combining in vivo optical imaging, molecular techniques, and ex vivo MRI, to investigate early capillary dysfunction in Tg-SwDI mice without memory impairment.

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  • The study explored the effectiveness of multidisciplinary rehabilitation (MDR) for individuals with multiple sclerosis (MS), highlighting the complexities of their symptoms and diverse treatment needs.
  • A randomized controlled trial was conducted with follow-up assessments focused on five main areas: Resilience, Cognitive Function, Energy, Physical Function, and Personal Needs, measuring outcomes using the Functional Assessment of Multiple Sclerosis (FAMS) tool.
  • Results showed significant improvements in FAMS scores at discharge for all focus areas, though the extent and durability of these improvements varied, underscoring the importance of tailored goal-setting in MDR for better health outcomes.
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Healthcare professionals experiencing barriers in the delivery of care are often unaware of factors within complex institutions that create and perpetuate those problems. Institutional ethnography in healthcare is a research methodology that starts from the perspective of a problem that clinicians or people receiving care experience and seeks to identify how those negative experiences are coordinated by institutional structures. This paper describes and advocates for the use of institutional ethnography as a powerful tool to investigate problems experienced by individuals or groups in the complex systems of healthcare design and delivery.

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Backyard chickens usually have open housing and scavenge for food, facilitating contact with infective forms of parasites present in the environment and increasing the risk of parasitic infections. Coccidiosis and ascaridiosis are two internal parasites in scavenging chickens that cause production losses to farmers. Prevalence data of these two diseases are scarce in low-income and middle-income countries (LMICs) but necessary to assess the burden of disease in backyard chickens.

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