CineECG analysis provides new insights into Familial ST-segment Depression Syndrome.

Aims: Familial ST-segment Depression Syndrome (Fam-STD) is a novel inherited cardiac disease associated with arrhythmias and sudden cardiac death. This study aimed at investigating the cardiac activation pathway in patients with Fam-STD, modelling the electrocardiogram (ECG) phenotype, and performing in-depth ST-segment analyses.

Methods And Results: CineECG analysis of patients with Fam-STD and age- and sex-matched controls.