Publications by authors named "Rashna Mirza"
Objective: The aim of this research study was to formulate a cost-effective, stable, less toxic and more efficacious intravenous nanoformulation that could rapidly augment the process of hemostasis.
Significance: Silver nanoparticles (AgNPs) evoked platelet activation, whereas alum (AM) neutralized the plasma proteins, causing blood coagulation. Tranexamic acid (TA) inhibited fibrinolysis and stabilized the formed blood clot.
Article Synopsis
- - Onychomycosis is a common fungal nail infection causing discoloration and detachment of nails, with increasing cases attributed to non-dermatophyte molds (NDMs) in warmer climates, alongside traditional dermatophytes.
- - Diagnosis is challenging due to high false-negative rates in standard methods, making histology and PCR more reliable, although they require careful handling to avoid contamination.
- - Treatment includes oral antifungals with better cure rates but more side effects, and topical options that are safer but less effective; ongoing research focuses on improving delivery methods and emphasizes the need for preventive measures to reduce reinfection rates.
Objectives: This research aimed to overcome challenges posed by cefepime excessive elimination rate and poor patient compliance by developing transdermal delivery system using nano-transfersomes based chitosan gel.
Methods: Rotary evaporation-sonication method and the Box-Behnken model were used to prepare cefepime loaded nano-transfersomes (CPE-NTFs). The physiochemical characterization of CPE-NTFs were analyzed including DLS, deformability index, DSC and antimicrobial study.