Sakuranetin and its therapeutic potentials - a comprehensive review.

Sakuranetin (SKN), a naturally derived 7--methylated flavonoid, was first identified in the bark of the cherry tree (s spp.) as an aglycone of sakuranin and then purified from the bark of . It was later reported in many other plants including , , spp.

Molecular modelling approaches predicted 1,2,3-triazolyl ester of ketorolac (15K) to be a novel allosteric modulator of the oncogenic kinase PAK1.

P21-activated kinases (PAKs) are serine/threonine protein kinase which have six different isoforms (PAK1-6). Of those, PAK1 is overexpressed in many cancers and considered to be a major chemotherapeutic target. Most of the developed PAK1 inhibitor drugs work as pan-PAK inhibitors and show undesirable toxicity due to having untargeted kinase inhibition activities.

A review on chemistry, source and therapeutic potential of lambertianic acid.

Lambertianic acid (LA) is a diterpene bioactive compound mainly purified from different species of . It is an optical isomer of another natural compound daniellic acid and was firstly purified from . LA can be synthesized in laboratory from podocarpic acid.

Artepillin C: A comprehensive review of its chemistry, bioavailability, and pharmacological properties.

Artepillin C (ARC), a prenylated derivative of p-coumaric acid, is one of the major phenolic compounds found in Brazilian green propolis (BGP) and its botanical source Baccharis dracunculifolia. Numerous studies on ARC show that its beneficial health effects correlate with the health effects of both BGP and B. dracunculifolia.