Publications by authors named "Rashid Kamal"

Article Synopsis
  • - Typhoid fever, caused by the bacteria Salmonella enterica serovar Typhi, is a serious health threat, especially with a new extensively drug-resistant (XDR) strain emerging in Sindh, Pakistan, characterized by unique genetic adaptations for antibiotic resistance.
  • - Researchers analyzed 58 ceftriaxone-resistant S. Typhi samples collected across Pakistan over two years using whole genome sequencing, discovering a variety of new genomic structures contributing to antibiotic resistance.
  • - The findings suggest that these resistant strains may acquire even more resistance genes, raising concerns about the potential for further spread and complicating public health efforts to control the outbreak.
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Pakistan is experiencing the first known outbreak of extensively drug-resistant (XDR) Salmonella enterica serotype Typhi (resistant to third-generation cephalosporins). The outbreak originated in Hyderabad in 2016 and spread throughout the Sindh Province. Whereas focus has remained on Sindh, the burden of XDR typhoid in Punjab, the most populous province, and the rest of the country is understudied.

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In the event of an influenza pandemic, vaccination will be the best method to limit virus spread. However, lack of vaccine biomanufacturing capacity means there will not be enough vaccine for the world's population. The U.

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