Publications by authors named "Rashid Halloway"
Purpose: Patients with sickle cell disease (SCD) may experience sickle cell-related pain crises, also referred to as vaso-occlusive crises (VOCs), which are a substantial cause of morbidity and mortality. The study explored how VOC frequency and severity impacts health-related quality of life (HRQoL) and work productivity.
Methods: Three hundred and three adults with SCD who completed an online survey were included in the analysis.
Background: This study aimed to evaluate sickle-cell disease (SCD) treatment patterns and economic burden among patients prescribed hydroxyurea (HU) in the US, through claims data.
Methods: SCD patients with pharmacy claims for HU were selected from the Medicaid Analytic Extracts (MAX) from January 1, 2009 - December 31, 2013. The first HU prescription during the identification period was defined as the index date and patients were required to have had continuous medical and pharmacy benefits for ≥6 months baseline and 12 months follow-up periods.
Sickle cell disease (SCD) is a life-threatening vascular disease that burdens affected persons physically. SCD-related vaso-occlusive crises (VOCs) are one of the primary causes of morbidity and mortality. Our objective was to examine the epidemiology of pain crises and the relationship between pain crises and major acute complications among SCD patients.
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- Sickle cell disease (SCD) is a serious chronic condition that significantly impacts quality of life due to painful crises, prompting the need for effective patient-reported outcome (PRO) instruments to evaluate treatments.
- A systematic literature review analyzed studies from 1997 to 2017, identifying 24 validated PRO instruments, but found that many lacked specific validation for SCD populations.
- The findings highlight a limited understanding of the psychometric properties of these instruments and underscore the need for better tools to facilitate future SCD clinical trials in the U.S.