A Study on Materials Used and Longevity of Implant-Supported Prostheses.

Objective: This retrospective research was directed to investigate the longevity and maintenance requirements of implant-supported prostheses in subjects treated at a tertiary care center.

Methods: Patient records of individuals who received implant-supported prostheses between January 2018 and December 2020 were retrospectively analyzed. Demographic information, implant type, prosthetic design, and follow-up data were collected.

Comparative Evaluation of Intracanal Smear Layer Removal by Different Root Canal Irrigants: A Scanning Electron Microscope Study.

Aim: The purpose of the study is to compare and evaluate the efficacy of different root canal irrigants-100, 75, 50, and 25% extract, 100, 75, 50, and 25% apple cider vinegar (ACV), a combination of 5.25% sodium hypochlorite (NaOCl) and 17% ethylenediaminetetraacetic acid (EDTA), and saline on smear layer removal using a scanning electron microscope (SEM).

Materials And Methods: A total of 80 freshly extracted single-rooted teeth were collected and divided into 10 groups-group I: normal saline (negative control), group II: NaOCl with EDTA (positive control), group III: 100% extract, group IV: 75% extract, group V: 50% extract, group VI: 25% extract, group VII: 100% ACV, group VIII: 75% ACV, group IX: 50% ACV, and group X: 25% ACV.

Comparative Evaluation of Reduction in Pain Perception Using 5% Topical LA vs Freezed Cone as a Preparatory Agent for Intraoral Injection in Children and Effect of VRD as Distraction Technique.

Aim: To compare freezed cone and 5% lignocaine as a numbing agent before intraoral injection and evaluate the effect of virtual reality distraction (VRD) as a distraction technique in reducing pain perception in children.

Study Design: Around 60 children of 6-11 years old undergoing treatment for the extraction or any pulp therapy of primary tooth were selected. Freezed cone and 5% lidocaine were used to decrease the pain during local anesthesia (LA).

Trends in surgery and survival for T1-T2 male breast cancer: A study from the National Cancer Database.

Background: Despite evidence that early-stage male breast cancer (MBC) can be treated the same as in females, we hypothesized that men undergo more extensive surgery.

Methods: Patients with clinical T1-2 breast cancer were identified in the National Cancer Database 2004-2016. Trends in surgery type and overall survival were compared between sexes.

Comparative Evaluation of Different Varnishes and Pit and Fissure Sealants on Count in Saliva of Children.

Aim: This study aims to evaluate and compare the effect of different varnishes: 3M ESPE Clinpro and Voco Profluorid and fissure sealants- 3M ESPE ClinPro and Ivoclar Vivadent Helioseal-F on the count in the saliva of children.

Materials And Methods: Eighty children of 6-12 years of age with no incidence of caries were selected and saliva samples were collected by drooling method after oral prophylaxis. The children were divided randomly into four groups and materials were applied accordingly.

The transcriptional response to oxidative stress is independent of stress-granule formation.

Cells respond to stress with translational arrest, robust transcriptional changes, and transcription-independent formation of mRNP assemblies termed stress granules (SGs). Despite considerable interest in the role of SGs in oxidative, unfolded protein and viral stress responses, whether and how SGs contribute to stress-induced transcription have not been rigorously examined. To address this, we characterized transcriptional changes in S2 cells induced by acute oxidative-stress and assessed how these were altered under conditions that disrupted SG assembly.

Efficacy of Silver Diamine Fluoride on Count Present in Saliva.

Aim And Objective: Evaluate the efficacy and longevity of silver diamine fluoride (SDF) to inhibit the dental caries initiator bacteria; count in saliva.

Study Design: Twenty children having class I and II dental caries with no prior restorations were included in the study. Unstipulated saliva samples were collected before and immediately after application of SDF, 1, 3, and 6 months after application, and intergroup comparison was done.

Management of invasive ductal carcinoma in hypermobile Ehlers-Danlos syndrome: a case report.

Literature is sparse regarding the management and long-term outcomes of breast cancer in patients with Ehlers-Danlos syndrome (EDS). Of the EDS subtypes, hypermobile Ehlers-Danlos Syndrome (hEDS) is associated with cardiovascular dysautonomia which manifests as spontaneous episodes of tachycardia and hypotension. Given this clinical autonomic system impact, hEDS is known to have significant intraoperative risk and postoperative complications.

Prevalence and Pattern of Hypomineralized Second Primary Molars in Children in Delhi-NCR.

Background: Developmental defects of enamel especially enamel hypomineralization are prevalent among children. Hypomineralized second primary molars (HSPM) present a serious clinical dilemma for the current practitioners. It represents as a potential predictive factor for molar incisal hypomineralization (MIH).

Comparative Evaluation of Antifungal Efficacy of Five Root Canal Sealers against Clinical Isolates of : A Microbiological Study.

Aim And Objective: The aim of this study was to evaluate and compare the antifungal efficacy of MTA Fillapex, Metapex, zinc oxide eugenol cement, Endomethasone, and Endoflas against .

Materials And Methods: Root canal exudates of 30 patients were tested against MTA Fillapex (Angelus), Metapex (BioMed), zinc oxide eugenol (Deepak Enterprise), Endomethasone (Septodont), Endoflas FS (Sanlor Laboratories), MTA (Angelus) (positive control), and glycerine (negative control). Children with failed endodontic cases were included in the study.

A Comparative Evaluation of Mechanical Properties of Four Different Restorative Materials: An Study.

Objectives: The purpose of this study is to compare the mechanical properties (compressive strength (CS) and diametral tensile strength (DTS)) of four different restorative materials: conventional glass ionomer (Fuji IX), ClearFil AP-X, Filtex Z350-XT, and Cention N.

Materials And Methods: Specimens ( = 80) were prepared from Fuji IX, ClearFil AP-X, Filtex Z350-XT, and Cention N for testing compressive strength and DTS.

Statistical Analysis: Results obtained were subjected to one-way ANOVA and Tukey's test at significance ( < 0.

Phase Ib/II single-arm trial evaluating the combination of everolimus, lapatinib and capecitabine for the treatment of HER2-positive breast cancer with brain metastases (TRIO-US B-09).

Background: Improving outcomes for patients with human epidermal growth factor 2-positive (HER2+) central nervous system (CNS) metastases remains an unmet clinical need. This trial evaluated a novel combination of everolimus, lapatinib and capecitabine for this disease.

Methods: Patients with trastuzumab-pretreated, HER2+ breast cancer brain metastasis without prior therapy with a mammalian target of rapamycin (mTOR) inhibitor were eligible.

Comparative Evaluation of Various Temperature Changes on Stress Distribution in Class II Mesial-occlusal-distal Preparation restored with Different Restorative Materials: A Finite Element Analysis.

Introduction: The principal goal of dentistry is to maintain and improve the quality of life of the dental patients. As many of these objectives require the replacement or alterations of the existing tooth structure, the main challenge for centuries has been the development and selection of biocompatible materials that can withstand the unique conditions of the oral environment.Finite element analysis (FEA) is a modern technique of numerical stress analysis that has become a solution to the task of predicting failure due to unknown stresses by showing problem areas in a material and allowing designers to see all of theoretical stresses within.