Incomplete peripheral retinal vascularisation in retinopathy of prematurity: is it the consequence of changing oxygen saturation?

Background: We wish to determine the prevalence and risk factors of incomplete peripheral avascular retina (IPAR) in children screened for retinopathy of prematurity (ROP) and its association with oxygen saturation (SpO) targets.

Methods: A retrospective review of retinal images of premature infants born and screened for ROP in Auckland Region, New Zealand, between January 2013 and December 2017 was conducted. Images were reviewed to determine if avascular retina was present at their final ROP screening.

Persistent Avascular Retina in Infants With a History of Type 2 Retinopathy of Prematurity: To Treat or Not to Treat?

Purpose: To investigate persistent avascular retina in infants with type 2 retinopathy of permaturity (ROP) that persisted after 45 weeks' post-menstrual age when regular ROP screening ceased.

Methods: A prospective observational study where fundus fluorescein angiography (FFA) was completed on consecutive infants who had a history of type 2 ROP and avascular retina during ROP screening that persisted after 45 weeks' post-menstrual age.

Results: FFA was completed on 72 eyes of 36 infants (53% male), with a mean gestational age of 26.

Outcomes of scleral-sutured conventional and aniridia intraocular lens implantation performed in a university hospital setting.

Purpose: To evaluate the outcomes of transscleral sutured posterior chamber intraocular lens (PC IOL) implantation.

Setting: Public university hospital, Auckland, New Zealand.

Design: Retrospective case series.

Regulation of connexin43 gap junction protein triggers vascular recovery and healing in human ocular persistent epithelial defect wounds.

Transiently blocking the expression of the gap junction protein connexin43 using antisense oligodeoxynucleotides or blocking hemichannels with connexin mimetic peptides has been shown to significantly improve outcomes in a range of acute wound models. Less is known about their likely effects in nonhealing wounds. In the eye, prolonged inflammation and lack of epithelial recovery in nonhealing corneal epithelial wounds may lead to corneal opacity, blindness or enucleation.

Prospective analysis of visual outcomes using apodized, diffractive multifocal intraocular lenses following phacoemulsification for cataract or clear lens extraction.

Background: To evaluate efficacy, safety and predictability of apodized, diffractive multifocal intraocular lenses.

Design: Prospective, observational study. PARTICIPANTS OR SAMPLE: Two hundred three patients (363 eyes) underwent surgery for cataract (54.

Alström syndrome--an uncommon cause of early childhood retinal dystrophy.

Alström syndrome (AS) is a ciliopathy and an uncommon cause of syndromic retinal dystrophy. This case reports findings in a 5-year-old boy with severe early onset retinal dystrophy, and how the recognition of extraocular features with genetic analysis led to the correct diagnosis of AS after 4 years of investigation.

Risk factors for age-related maculopathy.

Age-related maculopathy (ARM) is the leading cause of blindness in the elderly. Although beneficial therapeutic strategies have recently begun to emerge, much remains unclear regarding the etiopathogenesis of this disorder. Epidemiologic studies have enhanced our understanding of ARM, but the data, often conflicting, has led to difficulties with drawing firm conclusions with respect to risk for this condition.

Surgical and visual outcomes following exchange of opacified Hydroview intraocular lenses.

Aim: To report the clinical and surgical outcomes following exchange of opacified Hydroview intraocular lenses (IOLs), and to relate the final visual and anatomic results to clinical and surgical variables.

Methods: This is a prospective study of seventy-three eyes that underwent exchange of opacified Hydroview IOLs in Waterford Regional Hospital, Ireland. Preoperative, intraoperative and postoperative details were recorded.

Failure of Listeria monocytogenes keratitis to respond to topical ofloxacin.

Purpose: The purpose of this case report is to demonstrate the need for identification of the offending pathogen in bacterial keratitis to guide appropriate treatment.

Methods: Case report.

Results: We report a case of Listeria monocytogenes keratitis in a young healthy adult that failed to respond to standard empirical therapy for bacterial keratitis but was treated successfully with topical ampicillin, chloramphenicol, and systemic amoxicillin.