Publications by authors named "Rasha Alharthi"

Article Synopsis
  • The study investigates gene expression changes in response to different oxygen levels, comparing high altitudes to sea level.
  • Key genes involved, including VHLEL, VEGF, and HIF-1α, were found to be more active at high altitudes, suggesting a biological adaptation to low oxygen conditions.
  • The research contributes to understanding altitude sickness treatment and highlights the need for larger participant studies to enhance knowledge about physiological adaptations to low oxygen environments.
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Article Synopsis
  • - The study reviews the occurrence of phantom shocks (PSs) in patients with implantable cardioverter-defibrillators (ICDs), aiming to explore their incidence, risk factors, and management implications.
  • - It found that prior ICD shocks, defibrillation threshold testing, and mental health issues like depression and anxiety are significantly associated with the occurrence of PSs.
  • - The research emphasizes the need for healthcare providers to recognize these risk factors and deliver tailored care for patients dealing with PSs.
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The aim of this in vivo study was to compare total protein present in the salivary films (F) and acquired enamel pellicle (AEP) on eroded and non-eroded surfaces in patients suffering from GORD symptoms with and without GORD diagnosis (GORD, No-GORD). Thirty-nine patients suffering from GORD symptoms and erosive tooth wear on lower first molars and an unaffected posterior occlusal surface in the same quadrant were recruited from Guy's hospital, London. Salivary film and AEP were collected from the eroded and uneroded occlusal surfaces, using 0.

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  • The laboratory experiment aimed to enhance the mechanical properties of glass ionomer cement (GIC) by adding micron-sized silanized glass fibers (GFs) to the GIC luting powder.
  • Two concentrations of GFs (0.5% and 1.0% by weight) were tested, with the reinforced GICs evaluated for various mechanical and physical properties using advanced techniques like micro-CT.
  • The results showed that adding 0.5 wt.% GFs to Ketac Cem Radiopaque (KCR) GIC improved several mechanical properties without negatively affecting other physical characteristics, whereas the same addition to Medicem (MC) GIC had harmful effects.
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This laboratory investigation aimed to synthesize and characterize micron-sized Gum Arabic (GA) powder and incorporate it in commercially available GIC luting formulation for enhanced physical and mechanical properties of GIC composite. Oxidation of GA was performed and GA-reinforced GIC in 0.5, 1.

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Aim: This study aimed to evaluate the mechanical (i.e., flexural modulus [FM], flexural strength [FS], and surface roughness [R]) and antibacterial efficacy of photo-sonodynamic therapy via methylene blue-loaded poly(D,L-lactide-co-glycolide) nanoparticles (MB-loaded PLGA NPs) over dental implants for potential treatment of peri-implantitis.

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Amidst growing technological advancements, newer denture base materials and polymerization methods have been introduced. During fabrication, certain mechanical properties are vital for the clinical longevity of the denture base. This systematic review aimed to explore the effect of newer denture base materials and/or polymerization methods on the mechanical properties of the denture base.

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Background: Cancer associated thrombosis is recognized. However, pulmonary embolism (PE) from testicular cancer is rarely reported. Right ventricular (RV) function and PE are closely related.

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Platypnoea-orthodeoxia syndrome (POS) is defined by oxygen desaturation and dyspnoea in upright position that improves by lying down. It results from a right to left shunt at the intracardiac or intrapulmonary level. A 53-year-old ovarian cancer patient presented with POS that was refractory to oxygen therapy.

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Background: Cardiac lipomas are rare benign tumors commonly found in the right atrium or left ventricle. Patients are usually asymptomatic, and clinical presentation depends on location and adjacent structures impairment. Right ventricle lipomas are scarce in the literature.

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BACKGROUND Congenitally corrected transposition of great arteries (ccTGA) represents a distinct rare group of congenital heart diseases. Survival of unoperated ccTGA in the presence of large ventricular septal defect (VSD) is exceptional. Furthermore, late presentation of such patients in the absence of severe pulmonary hypertension or severe systemic right ventricle dysfunction is unusual.

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We present a symptomatic functional anterior mediastinal paraganglioma (PGL) in a 56-year-old woman. The patient was known to have renovascular resistant hypertension caused by fibromuscular dysplasia diagnosed several years ago. The diagnosis of PGL was confirmed by 123I-metaiodobenzylguanidine scintigraphy, 18F-FDOPA positron emission tomography/computed tomography and a thoracic tomographic scan which revealed an anterior mediastinal tumor.

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BACKGROUND Renal vein thrombosis is uncommon and can be associated with nephrotic syndrome. It is associated with high patient morbidity , and it may lead to thromboembolic event. CASE REPORT A 44-year-old woman presented with shortness of breath, chest pain and tightness, due to bilateral pulmonary embolism originating from right renal vein thrombosis.

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BACKGROUND Candida albicans is the principal human fungal opportunistic organism commonly detected in the gastrointestinal and genitourinary systems. Five species of candida (Glabrata, Tropicalis, Albicans, Parapsilosis, and Kruzei) are responsible for most cases of invasive candidiasis or candidemia, which is a growing public health concern due to the increasing complexity of patients, leading to a high fatality rate. CASE REPORT We report an extremely rare case of candida pericarditis due to esophagopericardial fistula in a young, heavy, alcoholic adult diagnosed by culture of the drained pericardial fluid, which showed a growth of Candida albicans.

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