Pyrazolopyrimidines: A promising frontier in cancer treatment- Reviewing their potential as inhibitors of serine/threonine kinases.

Pyrazolopyrimidine derivatives have emerged as potent inhibitors targeting a broad spectrum of kinases, particularly serine/threonine kinases. This review provides a comprehensive overview of the synthesis, structural modifications, and pharmacological relevance of pyrazolopyrimidine compounds in the realm of kinase inhibition. Specifically, the focus is placed on their inhibitory action against serine/threonine kinases, key players in cell signaling and potential therapeutic targets in various diseases, especially cancer.