Bioguided Isolation of Antibiofilm and Antibacterial Pregnane Glycosides from : Disarming Multidrug-Resistant Pathogens.

Methicillin-resistant (MRSA) and multidrug-resistant (MDRAB) present a serious challenge because of their capability to cause biofilm resistance to commonly used antibiotics producing chronic infections and hindering the process of wound healing. In the current study, we investigated the antibacterial activity of extracts (MeOH, and its fractions CHCl and -butanol) against multidrug-resistant MRSA USA300 and AB5057. In vitro, the MeOH extract and both fractions of significantly inhibited biofilm formation and disrupted previously established biofilm by MRSA and MDRAB at all the tested concentrations (0.

In vivo Antibacterial Activity of Star Anise ( Hook.) Extract Using Murine MRSA Skin Infection Model in Relation to Its Metabolite Profile.

Introduction: Star anise fruits ( Hook.) have been used as an important treatment in traditional Chinese medicine. The previous studies reported the activity of the non-polar fractions as potential sources of antibacterial metabolites, and little was done concerning the polar fractions of star anise.

Optimization and enhancement of textile reactive Remazol black B decolorization and detoxification by environmentally isolated pH tolerant Pseudomonas aeruginosa KY284155.

Azo dyes are complex derivatives of diazene used in food and textile manufacture. They are highly recalcitrant compounds, and account for severe environmental and health problems. Different strains of Pseudomonas species were isolated from textile wastewater effluents.

Fluoroquinolone resistant mechanisms in methicillin-resistant Staphylococcus aureus clinical isolates in Cairo, Egypt.

Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a persistent problem in community and health care settings. Fluoroquinolones are among the drugs of choice used to treat MRSA infections. This study aims to identify different mechanisms of fluoroquinolne resistance in local MRSA random sampling isolates in Cairo, Egypt.