Publications by authors named "Rares Eniu"
Spectrum of BRCA1/2 Mutations in Romanian Breast and Ovarian Cancer Patients.
Int J Environ Res Public Health
April 2022
Article Synopsis
- Approximately 10,000 women are diagnosed with breast cancer and 2,000 with ovarian cancer each year in Romania, but there are few genetic studies focused on identifying high-risk patients in the population.
- Researchers evaluated 490 women (250 with breast cancer and 240 with ovarian cancer) using Next-Generation Sequencing to examine for harmful mutations in the BRCA1 and BRCA2 genes.
- The study found a significant number of patients with BRCA mutations: 47% of breast cancer patients and 25% of ovarian cancer patients, identifying specific mutation variants that could help in genetic testing and risk assessment in the Romanian population.*