Publications by authors named "Raquel Virginia Rocha Vilela"

Background: SARS-CoV-2 virus originated in Wuhan (China) in December (2019) and quickly spread worldwide. Antigen tests are rapid diagnostic tests (RDT) that produce results in 15-30 min and are an important tool for the scale-up of COVID-19 testing. COVID-19 diagnostic tests are authorized for self-testing at home in some countries, including Brazil.

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Sporotrichosis is a superficial fungal disease that can affect animals and humans. The high number of infected cats has been associated with zoonotic transmission and contributed to sporotrichosis being considered by the World Health Organization as one of the main neglected tropical fungal diseases for 2021-2030. Oral administration of itraconazole (ITZ) is the first choice for treatment, but it is expensive, time-consuming, and often related to serious adverse effects.

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Some species of the fungus Sporothrix cause a chronic granulomatous infection in humans and animals called sporotrichosis. In the last decades, some research into serological tests has been carried out by different groups for the rapid detection of this infection. We performed a systematic review of the literature with meta-analysis to evaluate studies using Sporothrix spp.

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Article Synopsis
  • Cryptococcus gattii is a fungus that causes cryptococcosis, affecting both healthy and immunosuppressed individuals, and can lead to severe complications, including central nervous system infection.
  • Animal models are essential for studying how this fungus spreads and how the body responds, as well as for testing new treatments.
  • A new method using radiolabeled Cryptococcus gattii allowed for quicker detection of the fungus in mice, proving to be more effective for early infection stages compared to traditional culturing techniques.
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