Objective: The study analyzed people with HIV (PWH) measles seroprevalence and response to MMR booster given to seronegative individuals.
Design: A prospective cohort study with four groups: vertically (v-HIV), horizontally infected (h-HIV) individuals, and two control groups. An MMR booster was offered to seronegative individuals.
Background: Very limited data are available on the persistence of rubella antibodies in vertically HIV-infected individuals who were vaccinated early in life.
Methods: Prospective, cohort study on 4 groups of patients: 96 vertically HIV-1-infected individuals (v-HIV), 69 horizontally HIV-1-infected individuals (h-HIV), 93 healthy controls previously vaccinated for rubella (vac-CON) and 20 healthy controls with history of rubella disease (dis-CON). A blood sample was collected and rubella antibodies were analyzed by ELISA.