Publications by authors named "Raquel S Vale-Silva"
Article Synopsis
- - The IPP protein complex plays a critical role in the myelination process of oligodendrocytes, facilitating communication between cell receptors and the cytoskeleton through mechanical and biochemical signals.
- - Conditional gene ablation studies in mice highlight the unique function of the Pinch2 isoform, which prevents excessive myelination and aides in myelin stability, in contrast to the effects of Pinch1.
- - Pinch2 controls myelin formation by regulating RhoA and Cdc42 activities, indicating its essential role as a molecular hub in the signaling pathways necessary for proper oligodendrocyte development and myelin sheath integrity.
