Experimental Periodontitis Worsens Dopaminergic Neuronal Degeneration.

Aim: To investigate the hypothesis supporting the link between periodontitis and dopaminergic neuron degeneration.

Materials And Methods: Adult male Wistar rats were used to induce dopaminergic neuronal injury with 6-hydroxydopamine (6-OHDA) neurotoxin and experimental periodontitis via ligature placement. Motor function assessments were conducted before and after periodontitis induction in controls and 6-OHDA-injury-induced rats.