Publications by authors named "Raquel N de La Fuente"
Cholinergic stimulation with pyridostigmine improves autonomic function in infarcted rats.
Clin Exp Pharmacol Physiol
September 2013
In the present study we evaluated the effects of short-term pyridostigmine bromide (0.14 mg/mL) treatment started early after myocardial infarction (MI) on left ventricular (LV) and autonomic functions in rats. Male Wistar rats were divided into control, pyridostigmine, infarcted and infarcted + pyridostigmine-treated groups.
View Article and Find Full Text PDFRegarding all benefits of exercise training, a question remains: how long are these benefits kept? This study evaluated the effect of 3-week detraining after 10 weeks of training in STZ-diabetic rats. Male Wistar rats were assigned into: sedentary controls, trained controls, trained-detrained controls, sedentary diabetic, trained diabetic and trained-detrained diabetic. Arterial pressure (AP) and heart rate (HR) were recorded by a data acquisition system.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated heart rate responses and the effects of vagal electrical stimulation in rats after sinoaortic denervation, looking at both acute (1 day) and chronic (20 days) phases.
- In the acute phase, rats exhibited hypertension and tachycardia, while in the chronic phase, heart rate and blood pressure normalized, but blood pressure variability remained high.
- Chronic phase rats showed increased binding and affinity of muscarinic acetylcholine receptors, indicating that adaptations in the cardiac parasympathetic pathway occur as a response to baroreceptor disruption.