Early vs late enteral nutrition in pediatric intensive care unit: Barriers, benefits, and complications.

Background: This study aimed to define the existing barriers for early enteral nutrition (EEN) in critically ill children and to analyze the differences in nutrient supply, complications, and outcomes between EEN and late EN (LEN).

Methods: This is a secondary analysis of a multicenter observational, prospective study including critically ill children receiving EN. Variables analyzed included demographic and anthropometric features, caloric and nutrient supply, outcomes, and complications according to the EN onset.

Asymptomatic Cryptogenic Brain Abscess: A Case Report.

We report a case of a cryptogenic brain abscess in a 48-year-old immunocompetent male who was admitted for acute alcohol intoxication and a fall. A computed tomography scan (CT) of the brain showed a 10.5mm solitary mass in the parieto-occipital lobe.

Nutritional status and nutrition support in critically ill children in Spain: Results of a multicentric study.

Objectives: Critically ill children are often malnourished and require nutrition support (NS). Early enteral nutrition (EEN) seems to be safe in critically ill patients. However, there is a scarcity of data about the management of EEN in sick pediatric patients.

Protein phosphatases in chromatin structure and function.

Chromatin structure and dynamics are highly controlled and regulated processes that play an essential role in many aspects of cell biology. The chromatin transition stages and the factors that control this process are regulated by post-translation modifications, including phosphorylation. While the role of protein kinases in chromatin dynamics has been quite well studied, the nature and regulation of the counteracting phosphatases represent an emerging field but are still at their infancy.

CDK1 and PLK1 coordinate the disassembly and reassembly of the nuclear envelope in vertebrate mitosis.

Micronuclei (MN) arise from chromosomes or fragments that fail to be incorporated into the primary nucleus after cell division. These structures are a major source of genetic instability caused by DNA repair and replication defects coupled to aberrant Nuclear Envelope (NE). These problems ultimately lead to a spectrum of chromosome rearrangements called chromothripsis, a phenomenon that is a hallmark of several cancers.

Hydrogen-bonded networks in trans-3-(3-pyridyl)acrylic acid and rctt-3,3'-(3,4-dicarboxycyclobutane-1,2-diyl)dipyridinium dichloride.

The structure of trans-3-(3-pyridyl)acrylic acid, C(8)H(7)NO(2), (I), possesses a two-dimensional hydrogen-bonded array of supramolecular ribbons assembled via heterodimeric synthons between the pyridine and carboxyl groups. This compound is photoreactive in the solid state as a result of close contacts between the double bonds of neighbouring molecules [3.821 (1) A] along the a axis.

Analysis of irises with a latanoprost-induced change in iris color.

Purpose: To study the histologic aspects of irises subjected to extended latanoprost treatment.

Design: Prospective, observer-masked study.

Methods: Iris biopsies of eyes treated with latanoprost were analyzed (all had a photographically documented increase in iris pigmentation) plus control eyes (untreated with prostanoids) using optical microscopy.