Publications by authors named "Raquel Camargo-Camero"
Background: Ustekinumab (UST) is commonly used to treat Crohn's disease and ulcerative colitis. However, some patients may experience diminishing response or require increased dosage. Intravenous (IV) UST maintenance is explored as a solution.
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- - Inflammatory Bowel Diseases (IBD), like Crohn's disease, are chronic gut disorders influenced by genetic and environmental factors, including gene polymorphisms related to autophagy and non-steroidal anti-inflammatory drug (NSAID) usage.
- - NSAIDs can induce mitochondrial stress and mitophagy in intestinal cells, leading to the release of compounds that promote inflammation, particularly in the context of altered mitophagy seen in IBD patients.
- - Colonic organoids from Crohn's patients show an active mitochondrial Unfolded Protein Response (UPR) when treated with ibuprofen, suggesting that mitochondrial stress plays a significant role in IBD inflammation, especially in patients with varying disease activity.
Background And Objectives: The incidence of inflammatory bowel disease (IBD) in Spain has been traditionally lower than in Northern European countries. Recent epidemiological studies have found that these differences are diminishing. This study estimates the incidence of IBD in Málaga (Spain), a city in Southern Spain and relates its results to those found in our neighboring countries.
View Article and Find Full Text PDFBackground: The ideal length of treatment with thiopurines in patients with ulcerative colitis (UC) in sustained remission remains unknown. It is widely accepted that the drug withdrawal is associated with a worse outcome. The aim of this study was to analyze the outcome after this withdrawal and to identify predictors of relapse.
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