Publications by authors named "Raquel Aranega"
This study aimed to assess acute and residual changes in sprint-related hamstring injury (HSI) risk factors after a football (soccer) match, focusing on recovery within the commonly observed 72-h timeframe between elite football matches. We used a multifactorial approach within a football context, incorporating optical and ultrastructural microscopic analysis of BFlh (biceps femoris long head) muscle fibres, along with an examination of BFlh fibre composition. Changes in sprint performance-related factors and HSI modifiable risk factors were examined until 3 days after the match (MD ) in 20 football players.
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- - Inclusion Body Myositis (IBM) is an inflammatory muscle condition primarily affecting people over 50, leading to muscle weakness and diagnosed through clinical and histological evaluations.
- - Current challenges in IBM research include a lack of effective disease models, biomarkers, and treatments, prompting researchers to conduct an extensive analysis of biological samples from IBM patients.
- - The study found significant metabolic disturbances linked to IBM, particularly through abnormal levels of organic acids in samples, identifying L-pyroglutamic and orotic acid as potential biomarkers with 100% sensitivity and specificity, which need further testing in larger groups.
Article Synopsis
- Immune checkpoint inhibitors (ICI) improve cancer treatment but can trigger immune-related conditions, including dermatomyositis (DM).
- This study analyzed three DM cases linked to ICI from a patient cohort and reviewed existing literature on the topic.
- All cases were associated with specific ICI drugs and showed a strong presence of anti-TIF1γ autoantibodies, suggesting these antibodies may contribute to developing DM in some patients.