Upgrading skin barrier Protection: Addition of active ingredients to a Gelatin/Tannic Acid-Based hydrogel patch for treating skin lesions related to Personal protective Equipment.

Prolonged use of Personal Protective Equipment, like surgical masks, can cause skin issues such as acne ("maskne") and rosacea flare-ups due to pressure and moisture. While dressings can protect the skin, they often reduce mask effectiveness and lack pharmaceuticals to treat common skin lesions. This study introduces an innovative dual-function gelatin/tannic acid-based hydrogel patch incorporating metronidazole (1% w/w) or salicylic acid (2% w/w) to offer both skin protection and treatment.

High-fat diet during lactation, as opposed to during adolescence or gestation, programs cardiometabolic and autonomic dysfunctions in adult offspring.

The Developmental Origins of Health and Disease (DOHaD) concept has been established for three decades. Many studies have shown that, besides pregnancy, other plastic phases (mainly preconception, lactation, and infancy-adolescence) are also sensitive to environmental changes, including nutritional conditions, that can program health or disease later in life. This study compared the susceptibility of the gestation, lactation and adolescence to a high-fat diet (HFD) intervention to program rats into autonomic nervous system imbalance and cardiometabolic dysfunction in adulthood.

Hypertension induced by peri-pubertal protein restriction depends on renin-angiotensin system dysfunction in adult male rats.

Background And Aims: Hypertension depends on renin-angiotensin system dysfunction; however, little is known about its implications in the outcomes of neurogenic hypertension induced by peri-pubertal insults. This study aimed to evaluate whether hypertension induced by a peri-pubertal low-protein diet is related to renin-angiotensin system dysfunction in adult male Wistar rats.

Methods And Results: Thirty-day-old male Wistar rats were fed a low-protein diet (4 % casein) for 30 days and subsequently fed a 20.

Are native microalgae consortia able to remove microplastics from wastewater effluents?

Wastewater Treatment Plants (WWTPs) are potential sources of microplastics (MPs) in the aquatic environment. This study aimed to investigate the potential of wastewater-native microalgae consortia to remove MPs from the effluent of two different types of WWTPs as a dual-purpose solution for MPs mitigation and biomass production. For that purpose, the occurrence of MPs from two types of WWTP effluents was analysed over one year.

Validation of the Comprehensive Feeding Practices Questionnaire among parents of 5- to 7-year-old children in Sweden.

Introduction: Parents' behaviours towards food and mealtimes, also known as parental feeding practices, are important in the development of children's eating habits. The Comprehensive Feeding Practices Questionnaire (CFPQ) was designed to measure parental feeding practices. The aim of this study was to evaluate the validity of the CFPQ in Sweden and to assess how it performs across different groups of people.

Epigenetic programming for obesity and noncommunicable disease: From womb to tomb.

Several epidemiological, clinical and experimental studies in recent decades have shown the relationship between exposure to stressors during development and health outcomes later in life. The characterization of these susceptible phases, such as preconception, gestation, lactation and adolescence, and the understanding of factors that influence the risk of an adult individual for developing obesity, metabolic and cardiovascular diseases, is the focus of the DOHaD (Developmental Origins of Health and Disease) research line. In this sense, advancements in molecular biology techniques have contributed significantly to the understanding of the mechanisms underlying the observed phenotypes, their morphological and physiological alterations, having as a main driving factor the epigenetic modifications and their consequent modulation of gene expression.

Prevention of skin lesions caused by the use of protective face masks by an innovative gelatin-based hydrogel patch: Design and in vitro studies.

The recent Covid-19 pandemics led to the increased use of facial masks, which can cause skin lesions due to continuous pressure, tension and friction forces on the skin. A preventive approach is the inclusion of dressings between the face and the mask. However, there are still uncertainties about the protective effect of dressings and whether their use compromises the efficiency of masks.

Responsiveness in the Face of Sexual Challenges: The Role of Sexual Growth and Destiny Beliefs.

Implicit--or lay--sexual beliefs have been associated with how people respond to sexual challenges in romantic relationships. People who endorse s view a satisfying sex life as the result of finding the right partner and report poorer sexual, relationship, and personal well-being when there are sexual challenges. In comparison, people who endorse view satisfying sexual relationships as requiring hard work and effort to maintain and tend to report high sexual, relationship, and personal well-being even when facing sexual challenges.

Is Spontaneous Sex Ideal? Beliefs and Perceptions of Spontaneous and Planned Sex and Sexual Satisfaction in Romantic Relationships.

Sexual satisfaction is critical for relationship quality and people hold lay beliefs (implicit theories) about what makes for satisfying sex. A common belief in Western culture is that spontaneous sex is most satisfying, but this idea has not yet been studied. In pre-registered analyses of two studies - a cross sectional ( = 303 individuals) and a 21-day daily experience study ( = 121 couples) - we found support for two distinct beliefs (spontaneous sex as satisfying; planned sex as satisfying).

Health promotion at work: assessment of lifestyles of administrative assistants in a hospital.

Objective: To characterize the lifestyles of administrative assistants in a hospital, in order to define health promotion strategies in the workplace.

Method: A quantitative, descriptive, cross-sectional study, carried out with administrative assistants (N = 167) of a medium-sized Portuguese hospital. The data were collected through a questionnaire (QEV&PS-SO) for sociodemographic characterization and analysis of health determinants related to lifestyles.

Dialing up desire and dampening disinterest: regulating sexual desire in the bedroom and sexual and relationship well-being.

Romantic partners often regulate their emotions and affection to achieve certain goals, but research has yet to explore how partners regulate their expression of sexual desire during sex and its implications for couples' well-being. In two multi-part dyadic diary studies of primarily mixed-gender couples in longer-term relationships residing in North America, we examined three questions. First, is amplifying desire and suppressing disinterest during sex associated with both partners' daily sexual and relationship satisfaction? Second, do these associations differ by level of sexual desire and gender? Third, tested in our second sample, can these associations be explained by feelings of sexual inauthenticity? Across both samples (N = 225 couples, 450 participants), amplifying desire was associated with lower sexual satisfaction, while suppressing disinterest was not associated with daily satisfaction.

Non-gestational uterine choriocarcinoma inside a leiomyoma: importance of early suspicion in prognosis.

Uterine choriocarcinoma is a trophoblastic neoplasm most commonly related to pregnancy. However, there are already cases of non-gestational uterine choriocarcinoma (NGC) described in literature. The difficult diagnosis may delay treatment and threaten patient survival.

Opuntia ficus indica waste as a cost effective carbon source for lactic acid production by Lactobacillus plantarum.

Opuntia ficus indica (OFI) waste was evaluated as a fermentation feedstock for lactic acid production using Lactobacillus plantarum. Dilute acid pretreatment of the OFI cladodes (OFIC) was performed for extracting maximum fermentable sugars by optimizing process parameters using statistical optimization method. The best results were obtained with HCl 1% (v/v), temperature 120 °C, residence time 40 min, granulation 350 µm and substrate loading 5% (w/v), the sugar concentration reached 24 g/L with low concentration of hydroxymethylfurfural.

Leading Better Sex Lives: Is Trait Charisma Associated with Higher Sexual Desire and Satisfaction in Romantic Relationships?

Sexuality is a key predictor of relationship satisfaction, but sexual desire and satisfaction can be difficult to maintain over time. Past research has investigated who might be more likely to experience higher (compared to lower) levels of desire and sexual satisfaction in their relationships. Certain aspects of personality, such as extraversion, have been associated with sexual satisfaction and desire, but evidence linking personality to sexual outcomes has generally been mixed, meaning there is a lot left to learn about how personality is associated with sexual well-being.

IMplementation and evaluation of the school-based family support PRogram a Healthy School Start to promote child health and prevent OVErweight and obesity (IMPROVE) - study protocol for a cluster-randomized trial.

Background: IMPROVE aims to conduct a hybrid type 3 evaluation design to test the effectiveness of bundled implementation strategies on intervention fidelity of the Healthy School Start (HSS) program, while simultaneously monitoring effects on health outcomes of children and parents. The HSS is a 4-component family support program for children starting school (5-7 years of age) promoting healthy dietary habits and physical activity in the home environment to prevent childhood obesity and parents' risk of developing type 2 diabetes.

Methods: IMPROVE is a cluster-randomized controlled trial with two arms to evaluate and compare the effects of two different bundles of implementation strategies on intervention fidelity expressed as adherence and responsiveness at 12 and 24 months (primary outcomes).

Comparative Study of the Antioxidant and Enzyme Inhibitory Activities of Two Types of Moroccan Entire Honey and Their Phenolic Extracts.

Honey is a natural food product very famous for its health benefits for being an important source of antioxidant and phenolic compounds. honeys obtained from different regions of Morocco were evaluated for their ability to inhibit acetylcholinesterase, lipoxygenase, tyrosinase and xanthine oxidase activities. Their antioxidant properties were evaluated using the: 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging capacity, nitric oxide scavenging activity (NO) and scavenging ability of superoxide anion radical.

Prognostic relevance of exercise testing in hypertrophic cardiomyopathy. A systematic review.

Background: Cardiopulmonary exercise test (CPET) is indicated as part of the assessment in hypertrophic cardiomyopathy (HCM) patients and stress echocardiography is often used to assess symptoms. However, the role of exercise testing for prognostic stratification in HCM is still not established.

Aims: To systematically review the evidence on the role of exercise testing for prognostic stratification in hypertrophic cardiomyopathy.

Biochemical Characterization of the Amylase Activity from the New Haloarchaeal Strain sp. HS Isolated in the Odiel Marshlands.

Alpha-amylases are a large family of α,1-4-endo-glycosyl hydrolases distributed in all kingdoms of life. The need for poly-extremotolerant amylases encouraged their search in extreme environments, where archaea become ideal candidates to provide new enzymes that are able to work in the harsh conditions demanded in many industrial applications. In this study, a collection of haloarchaea isolated from Odiel saltern ponds in the southwest of Spain was screened for their amylase activity.

Complying with the Guideline for Quality and Equivalence for Topical Semisolid Products: The Case of Clotrimazole Cream.

Semisolids constitute a significant proportion of topical pharmaceutical dosage forms available on the market, with creams being considered profitable systems for releasing active substances into the skin. This work aimed at the development of a generic Clotrimazole topical cream, based on the assumptions that assist the development of such formulations. First, the critical parameters to obtain a final formulation as similar as possible to the reference product were defined.

Perceived partner sexual responsiveness buffers anxiously attached individuals' relationship and sexual quality in daily life.

Satisfying relationships are central to health and well-being, yet the insecurities of anxiously attached people can detract from the quality of their romantic relationships. One factor associated with relationship quality is perceiving a partner as responsive to one's needs, and responsiveness to a partner's needs might be a particularly powerful way to signal responsiveness to anxiously attached partners. In a 21-day daily experience and longitudinal study of 121 couples, we tested perceived partner sexual responsiveness as a buffer against the lower relationship quality (satisfaction, commitment, trust) and sexual satisfaction that anxiously attached people typically experience.

Navigating Women's Low Desire: Sexual Growth and Destiny Beliefs and Couples' Well-Being.

People's beliefs about how to maintain sexual satisfaction have been associated with how they navigate sexual differences, but research has yet to explore the consequences of these beliefs for couples facing a distressing sexual issue. The current research extends past work on sexual growth beliefs (i.e.

The detriments of unmet sexual ideals and buffering effect of sexual communal strength.

Despite the importance of sex for the maintenance of satisfying romantic relationships, our understanding of a person's sexual ideals-the traits and attributes a person desires in a sexual partner or experience-and what might buffer against lower satisfaction associated with unmet sexual ideals is limited. Across four studies including cross-sectional, dyadic, longitudinal, and experimental methods (N = 1,532), we draw on the Ideal Standards Model and theories of communal motivation to examine whether unmet sexual ideals are associated with lower sexual satisfaction and relationship quality and test whether higher sexual communal strength-the motivation to meet a partner's sexual needs-buffered these effects. Across studies, when individuals perceived their partner to fall short in meeting their sexual ideals, they reported poorer sexual and relationship quality.

Avoidantly Attached Individuals Are More Exchange-Oriented and Less Communal in the Bedroom.

Sexual need fulfillment in a relationship is associated with both partners' sexual and relationship quality. In the current research, we explored what underlies two approaches to sexual need fulfillment-sexual communal norms (i.e.

Antioxidant activity and enzyme inhibitory potential of Euphorbia resinifera and E. officinarum honeys from Morocco and plant aqueous extracts.

Natural products may be applied in a wide range of domains, from agriculture to food and pharmaceutical industries. In this study, the antioxidant properties and the capacity to inhibit some enzymatic activities of Euphorbia resinifera and Euphorbia officinarum aqueous extracts and honeys were assessed. The physicochemical characteristics were also evaluated.

Leveraging goals to incentivize healthful behaviors across adulthood.

Despite abundant evidence for the benefits of physical activity on aging trajectories, older Americans remain largely inactive. The present study was designed to examine age differences in responsiveness to financial incentives to increase walking. Grounded in socioemotional selectivity theory, we examined the effectiveness of financial incentives that varied in prosociality.