Research into tumorigenic pathways can aid in the development of more efficient cancer therapies and provide insight into the physiological regulatory mechanisms employed by rapidly proliferating cancer cells. Due to the severe side effects of cancer chemotherapeutic medications, plant chemicals and their analogues are now explored more frequently for the treatment and prevention of colorectal cancer (CRC), opening the stage for new phytotherapeutic strategies that are considered effective and safe substitutes. Our study aimed to evaluate the medicinal properties of L.
View Article and Find Full Text PDFRecently, the field of epigenetics has been intensively studied in relation to nutrition. In our study, the gene expression patterns of histone deacetylases (s), which regulate the stability of histone proteins, and DNA methyltransferases (s), which regulate DNA methylation, were determined in mice. The animals were fed a human-equivalent dose of the aqueous extract of fruit seeds and peels, which is rich in flavonoids and polyphenols, for 28 days and then exposed to the carcinogen 7,12-dimethylbenz(a)anthracene (DMBA).
View Article and Find Full Text PDFEven though the pathophysiology of colorectal cancer (CRC) is complicated and poorly understood, interactions between risk factors appear to be key in the development and progression of the malignancy. The popularity of using lactic acid bacteria (LAB) prebiotics and probiotics to modulate the tumor microenvironment (TME) has grown widely over the past decade. The objective of this study was therefore to determine the detrimental effects of LAB-derived lactic acid in the colonic mucosa in colorectal cancer management.
View Article and Find Full Text PDFBiomed Pharmacother
March 2022
Mushroom consumption has grown extraordinarily owing to their high nutritional value, desirable taste, and aroma. Mushrooms continue generating lots of interest chiefly in their consumption as food, as a cure for different ailments, as well as important goods for commerce throughout the globe owing to their dietary, antioxidant, and therapeutic values. Higher Ascomycetes and Basidiomycetes mushrooms have different properties with anticancer and immunological potential.
View Article and Find Full Text PDFMedicinal plant species contain vast and unexploited riches of chemical substances with high medical potential making these plant species valuable as biomedicine sources. Cassia fistula L is an important medicinal plant used in many traditional medicinal systems including Ayurveda and Chinese Traditional Medicine. It is a deciduous medium sized tree with elongated and rod-shaped fruits having pulp and have bright yellow flowers, earning the name 'Yellow Shower'.
View Article and Find Full Text PDFRecent research findings support the assumption that the development of chronic diseases in adults is greatly influenced by the supply of nutrients in the uterus and the nutrition, nourishment of the early, toddler ages. The aim of the present study was to evaluate the nutritional habits of infants and toddlers aged 0-3 in Hungary, and to identify the most typical problems of their nutrition, to get to know and provide the necessary data for the modification and modernization of feeding/nutrition recommendations for infants and young children in Hungary. The study was carried out with the professional coordination of the Hungarian Dietetic Association (MDOSZ) in the framework of industry research between June and August 2015, in the 0-3-year-old population, in the cities Budapest, Debrecen, Győr, Szeged and Pécs.
View Article and Find Full Text PDFBackground And Purpose: Objective - Our aim is to evaluate sleep habits, sleep quality and influencing factors among preschool- and schoolchildren.
Methods: Two questionnaires were recorded. Questionnaire 1 dealt with sleeping habits, breastfeeding and health behavior of preschool children and infant, and it contained the abbreviated version of the Children's Sleep Habits Questionnaire.
The impact of one-day surgery has been increasing since the past few decades. This type of health service could fulfil many requirements of health policy, health care services, governments as well as patients. The aim of the research was to assess the publicly financed case numbers and interventions of one-day surgery in Hungary between 2010 and 2015 from different aspects.
View Article and Find Full Text PDFIntroduction: Several studies have demonstrated that the prevalence of heart disease can be accounted for between 0.4 and 2% in developed countries.
Aim: The present study aimed to use the PA% of the telemetry data to estimate the 6-minute walk test result.
Introduction: The effect of regular physical activity on health is widely recognized, but several studies have shown its key importance for heart patients.
Aim: The present study aimed to define the PA % values, and to convert them into metabolic equivalent values (MET), which describes oxygen consumption during physical activity.
Method: A total of seventeen patients with heart disease; 3 females and 14 males; age: 57.
Introduction: Nowadays, the food industry more often uses different type of additives during the food production.
Aim: Our aim was to examine the monosodium-glutamate's effect (in animal experiment) on DNA-methyltransferases in gene expression patterns of mRNA levels.
Materials And Method: In the investigation we used 24 (n=24) CD1 type female mice.
Plant-based diet is an old-new trend in nutrition. In this review based on a historical context, we wish to introduce this popular nutritional trend. Our aim is to present plant-based diet as a primary measure for prevention.
View Article and Find Full Text PDFIntroduction: Among Hungary's health sector workers the presence of a high level of stress is known, which can affect the individual.
Aim: The aim of the authors was to uncover major risk factors causing work-related stress, as well as its extent, and positive and negative coping strategies among ground and aerial rescue workers.
Method: From June until October 2015, a national survey was conducted among Hungarian rescue workers.
Introduction: An increasing motivation can be experienced among professional workers within the Hungarian healthcare system towards foreign employment or career change.
Aim: The aim of the authors was to assess Hungarian physiotherapists' migration and career changing behaviour and to understand the underlying factors.
Method: A national survey in Hungary from April to August, 2014 was performed.