Publications by authors named "Raphaela A Chiareli"
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Synopsis of recent research by authors named "Raphaela A Chiareli"
- Raphaela A Chiareli's research focuses on neuroprotection and the mechanisms of neurotransmitter transporters, especially Glycine Transporter Type 1 (GlyT1) and its interaction with NMDA receptors in cerebral damage and schizophrenia models.
- Her studies indicate that inhibiting GlyT1 enhances neuroprotection by increasing synaptic glycine levels, while exploring the potential of proline transporter inhibitors like LQFM215 to improve glutamatergic neurotransmission and exhibit antipsychotic effects.
- Chiareli's work emphasizes the role of neurogenesis and astrocyte function in brain repair processes, particularly following ischemic stroke, highlighting the dynamic interplay between neurotransmission, neuroinflammation, and neurogenesis in recovery outcomes.