Publications by authors named "Raphael Chouteau"
Article Synopsis
- Over the past decade, the number of approved drugs for treating Multiple Sclerosis (MS) has expanded from 3 to 10, allowing for more personalized treatment strategies aimed at minimizing clinical and radiological progression of the disease.
- The paper outlines a comprehensive workflow designed for monitoring new FLAIR lesions in MS patients using longitudinal MRI scans, targeting usability for neurologists and radiologists in France.
- Evaluation results indicate that the new workflow significantly improved lesion detection accuracy and reduced the analysis time for experts, suggesting enhanced capability in classifying MS patients' disease status.
Despite important efforts to solve the clinico-radiological paradox, correlation between lesion load and physical disability in patients with multiple sclerosis remains modest. One hypothesis could be that lesion location in corticospinal tracts plays a key role in explaining motor impairment. In this study, we describe the distribution of lesions along the corticospinal tracts from the cortex to the cervical spinal cord in patients with various disease phenotypes and disability status.
View Article and Find Full Text PDFBackground: In patients with MS, the effect of structural damage to the corticospinal tract (CST) has been separately evaluated in the brain and spinal cord (SC), even though a cumulative impact is suspected.
Objective: To evaluate CST damages on both the cortex and cervical SC, and examine their relative associations with motor function, measured both clinically and by electrophysiology.
Methods: We included 43 patients with early relapsing-remitting MS.