Publications by authors named "Raoshan Luo"
Introduction: This systematic review and network meta-analysis(NMA) was designed to compare the long-term outcomes of pembrolizumab monotherapy and pembrolizumab plus chemotherapy as first-line therapy for metastatic non-small-cell lung cancer(NSCLC).
Materials And Methods: Four databases(Medline, Embase, Web of Science and CENTRAL were searched published from establishment of database to August 17, 2023, for articles studying pembrolizumab monotherapy or pembrolizumab plus chemotherapy for non-small cell lung cancer (NSCLC). Network meta-analyses of progression-free survival(PFS), overall survival(OS), objective response rate(ORR), treatment-related adverse events(trAEs) and immune-related adverse events(irAEs) were performed.
Purpose: To compare the efficacy and safety of micropercutaneous nephrolithotomy (MPCNL) and flexible ureteroscopy (FURS) in the treatment of single upper ureteral calculi measuring 1 to 2 centimeters.
Methods: This study is a retrospective analysis that combines a review of medical records with an outcomes management database. A total of 163 patients who underwent MPCNL and 137 patients who had FURS were identified between January 2017 and December 2021.
Introduction: This meta-analysis aims to evaluate the efficacy and safety of neoadjuvant PD-1 inhibitors or PD-L1 inhibitors [PD-(L)1 inhibitors] for muscle-invasive bladder carcinoma (MIBC).
Materials And Methods: Four databases (Medline, Embase, Web of Science, and 21 CENTRAL) were searched for articles studying neoadjuvant PD-(L)1 inhibitors for MIBC. The search time period was from the establishment of each database to 21 July 2023.
Introduction: Previous studies have compared robot-assisted thoracic surgery(RATS) with video-assisted thoracic surgery (VATS) in the treatment of patients with lung cancer, but results were conflicting. The present meta-analysis aimed to compare the clinical outcomes of RATS with VATS in the treatment of patients with lung cancer.
Materials And Methods: Web of Science, PubMed, Cochrane Library and Embase were comprehensively searched for randomized controlled trials or prospective cohort studies comparing the clinical outcomes of RATS and VATS from inception to 22 July 2023.
Introduction: There is still controversy on whether or not robot-assisted colorectal surgery (RACS) have advantages over laparoscopic-assisted colorectal surgery(LACS).
Materials And Methods: The four databases (PubMed, Embase, Web of Science and Cochrane Library)were comprehensively searched for randomized controlled trials (RCTs) comparing the outcomes of RACS and LACS in the treatment of colorectal cancer from inception to 22 July 2023.
Results: Eleven RCTs were considered eligible for the meta-analysis.
Article Synopsis
- - The study investigates treatment outcomes for displaced femoral neck fractures in older adults, comparing total hip arthroplasty (THA) and hemiarthroplasty (HA) among 139 patients treated between 2015 and 2017.
- - Results show that THA involves longer surgery times, more blood loss, and longer hospital stays, but both procedures had similar complication rates and survival rates after five years.
- - Five years post-surgery, THA patients demonstrated significantly better hip function scores compared to HA patients, indicating enhanced recovery in mobility and pain relief.
Article Synopsis
- The study evaluated the effectiveness and safety of anti-interleukin-1 treatments for knee osteoarthritis by systematically reviewing randomized controlled trials from various databases up until August 2022.
- Results indicated that these therapeutics were more effective than a placebo in reducing pain and improving function, although there was an increase in the overall incidence of adverse effects compared to placebo.
- Specific anti-interleukin-1 therapies, especially IL-1 antibodies and inhibitors, showed significant benefits, while IL-1 receptor antagonists did not demonstrate similar efficacy, highlighting the varying effectiveness among different treatment types.