Publications by authors named "Rao-Li He"
Genetic epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis.
J Neurol Neurosurg Psychiatry
July 2017
Article Synopsis
- - The study analyzed mutation frequencies of key genes associated with amyotrophic lateral sclerosis (ALS) by reviewing 111 research articles and combining their data.
- - The results indicated that mutation frequencies were significantly higher in familial ALS (47.7%) compared to sporadic ALS (5.2%), with notable differences between European and Asian populations in the types of mutations observed.
- - The findings highlight that the genetic characteristics of ALS differ between Asian and European patients, which is important for tailored genetic testing and treatment approaches.